Protein Alignment by and tns2

DIOPT Version :10

• Sequence 1: NP_649901.1
• Gene: by / 41144
• FlyBaseID: FBgn0000244
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: XP_002936689.3
• Gene: tns2 / 100486792
• XenbaseID: XB-GENE-988669
• Length: 1850
• Species: Xenopus tropicalis
• Alignment Length: 821
• Identity: 228/821 - (27%)
• Similarity: 340/821 - (41%)
• Gaps: 239/821 - (29%)

  Fly     6 EESAAAADHKYQYQ--YTAANNNNNYYKNYNVNGNGQ-----ANGNGNLSGIGNGNGIGNGNGYG 63
            :.|.|:..|....|  :||..::    .:..:||:.|     ..|:|.|..: :..|....|
 Frog  1147 QTSPASPTHSPSSQTGHTAQLSS----PSVQLNGSSQHMSLAVQGHGQLHSL-DERGQAQDN--- 1203

  Fly    64 IPYHARENSLPFSYGIAKTSTPLRKTPTPTRVDSFLDFDFGPTNTNVNSNSSSNNGGTGDMIKPP 128
            :|.|    ||.|                             |||..||:.||.:...    |...
 Frog  1204 VPTH----SLTF-----------------------------PTNNPVNTKSSPDQSD----ISNH 1231

  Fly   129 TRLTSPLLVRKTLGNAVSPTSSTNTNTIA----NTY----HYTSSSATPTPVRDNFEQLLRERRE 185
            |:.||     |.:.|...|:.....|.:|    |:|    ::|..|...|||...|.....:|
 Frog  1232 TQNTS-----KEVHNTALPSEPQTGNCVARQITNSYPHSPNHTHISEDQTPVTTAFALTETDR-- 1289

  Fly   186 KVYNEYRNLDRESSGERARVAPAPPQRQYYPSDGYGIGLKNDSNGTLYRKSPSSNGKSTKYNYDF 250
                                    ||::...|                ..|.|.|..|
 Frog  1290 ------------------------PQQKMVQS----------------HSSVSVNNSS------- 1307

  Fly   251 EFNLNLDDVRPEPTPYTTRNIHFEDLRLDQDVPDGVVNRRTMERNYHTINSLETTHKRQQLEPLE 315
                    |:|..|.:|...:...|..::..:|...::....:.:...::|  |.|       .:
 Frog  1308 --------VKPYSTVHTQSQLVQTDNSIESQIPPVQLHHPVPKASQAQLHS--TVH-------TQ 1355

  Fly   316 QLGAVYGQN-----------HMEETLTRTRRDLSAS--------------TSTSKSTSPLPAIGV 355
            ....|.||:           |...|:...|..|.|:              ..||.|.|.:....:
 Frog  1356 LYRTVGGQSPSVPTQKPVPTHPNSTVVTERPGLPATHVNAPPCANEANTLLPTSSSQSHVTKFVL 1420

  Fly   356 PAIAPASPIYATSTKRVSNPNTN--------GQQQMTPSPT----SRPETPAFPVTPRTPFGASS 408
            |..:.|...:.|....:|:|:..        .|....|..|    .|..|.:.||:|..|.|..:
 Frog  1421 PVTSEAKRSHTTFGPAISSPSGTTAFGSGYCSQSFSVPKHTVLLQKRSVTISLPVSPVNPQGKEA 1485

  Fly   409 SSSASLAP----TTQLPPE---------SIYQTGPRRGVPPALQPLEV------SADSVQ----- 449
            .:|...:|    :..|||.         :.|.:.|   .||::||..:      .||..:
 Frog  1486 PTSPPKSPMGSQSDLLPPSPTPSFPIRTAYYSSSP---CPPSIQPPRLPEKNHSPADGAKVDPNG 1547

  Fly   450 -----------------------FARSSSQFWYKPNLTREDAIALLASAQPGTFLVRDSTTYKDS 491
                                   |.:.||:|||||.::||.|||:|..|:||:||:|||.:::.:
 Frog  1548 LSECNKGHSSPVDTQQDVPVTGNFVQDSSKFWYKPTISREQAIAILRGAEPGSFLIRDSNSFRGA 1612

  Fly   492 YGLVVRVSQPPP----------GSQELVRHFLIEPTKGGVHLKGCDDEPVFTSLSALVFEHSISQ 546
            |||.::|:.|||          .:::||||||||....||.:||...||.|.||||||.:||::.
 Frog  1613 YGLALKVASPPPNVAAQPYKGDSTEQLVRHFLIETGPKGVKIKGSPIEPHFGSLSALVSQHSVTP 1677

  Fly   547 LALPCLLRLPDRDIVP-------PVRATTPAQQHLLAHGAATNVLWLYSCDTESLTGNEAIRKAI 604
            |:|||.|::|.||::.       |...:|.|.  ||..|||.:||:|.|.|||||||.:||.:|.
 Frog  1678 LSLPCRLQIPSRDLIEQSSEVMVPTNMSTAAD--LLRQGAACSVLYLGSVDTESLTGPQAISRAS 1740

  Fly   605 RQMYGQQPLPQPTEVHFKVSSQGITLTDNTRKKFFRKHYKADVISHCAIDPENRMWTSEGESDKK 669
            ..:. ..|....|.||||||.|||||||:.||.|||:||....::.|..||::|.||:...:..|
 Frog  1741 NAIL-TPPRSSATTVHFKVSDQGITLTDSQRKLFFRRHYPVSSVTFCNSDPQDRRWTNPDRTTSK 1804

  Fly   670 TIFAFVARRSHSSTDNQCHVFCDLSVSQPAAAIVSFANRTL 710
             :|.||||::.::.:|.||:|.:|...|||:|||:|..:.:
 Frog  1805 -VFGFVARKAGTAAENVCHLFAELDPEQPASAIVNFITKVM 1844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
by	NP_649901.1	SH2_Tensin_like	454..559	CDD:198181	57/114 (50%)
		PTB_tensin	578..711	CDD:269924	63/133 (47%)
tns2	XP_002936689.3	C1_TNS2	30..82	CDD:410437
		PTP_tensin-2	130..288	CDD:350410
		PTEN_C2	300..424	CDD:463081
		PHA03247	<859..1170	CDD:223021	6/26 (23%)
		Herpes_BLLF1	<1040..1527	CDD:282904	96/498 (19%)
		SH2_Tensin_like	1575..1690	CDD:198181	57/114 (50%)
		PTB_tensin	1714..1845	CDD:269924	63/133 (47%)