Protein Alignment Kdm3 and kdm3b

DIOPT Version :10

• Sequence 1: NP_788611.1
• Gene: Kdm3 / 41143
• FlyBaseID: FBgn0037703
• Length: 854
• Species: Drosophila melanogaster
• Sequence 2: XP_005173195.2
• Gene: kdm3b / 326643
• ZFINID: ZDB-GENE-101007-4
• Length: 1824
• Species: Danio rerio
• Alignment Length: 962
• Identity: 359/962 - (37%)
• Similarity: 485/962 - (50%)
• Gaps: 207/962 - (21%)

  Fly    56 ENPTLKAEQRVQQEEESLGQVPPLTE---------EEQQRHDEFRNSGSIFLQDLPCFKLQQAQP 111
            :.|.|.|....:.:.::..:..|.::         ::|.:....:.||..||||..|..:
Zfish   879 QKPDLPAGNEDKNKAQAAAKSRPRSKPFKVGQSVLKDQNKVRRLKQSGEAFLQDGSCINV----- 938

  Fly   112 IAGSSPIPKCRECRRRNLATTEGEPSSVSD--VYCRFYEFRRLQFNENGELCVVGFPNPYSEPSP 174
               :..:.||||||......:..:.|...|  |.|||:.||||.|.:.|.|.|.||.:|....|.
Zfish   939 ---APHLHKCRECRLERYRKSREQDSDDDDPNVACRFFHFRRLAFTKKGVLRVEGFLSPQQSDSM 1000

  Fly   175 EDIAIWQPDKNTPPTSGYMDIQVCRYILLHAGDQFCYIWHQEAEALSL---HQNTDGTIAWKKAV 236
            . :.:|.|.......   :|:...:|||.:.|||||.:...|.||:.:   ||.    :|||:||
Zfish  1001 A-MGLWLPSITIQEG---LDLDTSKYILANVGDQFCQLVMSEKEAMMMVEPHQK----VAWKRAV 1057

  Fly   237 KGTREICDVCDTTLFNYHWTCRKCGFGVCLDCVKDRKEGLRLRRAENAAQKGCDEYHWLLCS--D 299
            :|.||:||||:|||||.||.||||||||||||.:.||.  |....|:..::  :.:.||.|:  .
Zfish  1058 RGVREMCDVCETTLFNIHWVCRKCGFGVCLDCYRLRKN--RPPEVEDGPEE--EVFSWLKCAKGQ 1118

  Fly   300 PSGPQEHVLTELMLTQIIAGDALNVLGRLLHEVRTLWQVPQVCGC-------------------- 344
            |..||     .||.||||.|.||..:|.::|..|..|.:...|.|
Zfish  1119 PHEPQ-----NLMPTQIIPGTALYSIGDMVHAARGKWGIKANCPCTSRHKTLMRPSAPNGLSQSG 1178

  Fly   345 --------------------------LLSKQAIEDAQSKEVIQD--------------------- 362
                                      ::..:.:|:..|.:....
Zfish  1179 AAHSSGNGTTSTSSTTRPNEESAAGVVVKTEPVEEPTSADTTSSTSGTNSSTSSPAPAPTSAPTL 1243

  Fly   363 --------------------MIKESQLKQHTSYSS-------LASEQKVHQQQR----------- 389
                                ::.....|...|.||       ||::::..:..|
Zfish  1244 LPPSLPPPSLPPPSLPPAPALVPTPPAKDSKSSSSALHWLADLATQKEPKESLRSMMGRDSRSPF 1308

  Fly   390 -LDQL--------HATKLEFARELG----------------VDYVPGRVWTKETLGKDPITTAFD 429
             ||..        .:.||..:..||                ::...|::....|.|..|....|.
Zfish  1309 GLDSFSTLSKPSGSSPKLFNSLLLGAGPSQPKAEGTSLRDLLNSGSGKLPQGPTEGGVPFPPVFS 1373

  Fly   430 NLKHINFLRKGL----------------AGLRR-----------FLPPRTMTFAYSTQLAPGVPH 467
            .....:.::.||                :.:||           ..|.|......|. |.|...|
Zfish  1374 TASQADKMKGGLPNFLDHIIASVVETKKSEVRRASGSAEVIESATAPRREGVMGLSV-LDPHTSH 1437

  Fly   468 EFLCDGRLLRLTDAMHPDNRVLFQEVWKCGQPVMISEVARSLNLDLWHPQAFCRDFGDKPNDLIN 532
            .:|||||||.|.|..:|:|..:|:|.||.||||::|.:.|.|...||.|:||..:|||:..||:|
Zfish  1438 SWLCDGRLLCLQDPSNPNNWKIFRECWKQGQPVLVSGIHRKLKEHLWRPEAFSEEFGDQDVDLVN 1502

  Fly   533 CLNGNLVPNQPMRHFWEGFQCMTKRLPDAYGKPMLLKLKDWPPGDDFAEILPTRFADLMKGLPMP 597
            |.|..::.:..:|.||:|||.::|||..:.|:||:|||||||||:||.:::||||.|||..||:|
Zfish  1503 CRNCAIISDVKVREFWDGFQVISKRLQGSDGQPMVLKLKDWPPGEDFRDMMPTRFNDLMDNLPLP 1567

  Fly   598 EYTLRTGNLNIASCLPKMFVPPDLGPKMYNAYGSALHPDK--GTTNLHLDISDAVNIMVYVGIPQ 660
            |||.|.|.||:||.||..||.||||||||||||.....|:  ||||||||:|||||:|||||||:
Zfish  1568 EYTKRDGRLNLASRLPNFFVRPDLGPKMYNAYGLISTEDRKVGTTNLHLDVSDAVNVMVYVGIPE 1632

  Fly   661 ---DGDTRPQMAA---TQKAIEIGGCDYITRARCQSPDVLPGALWHIFPARDADKIRDLLNRVTL 719
               |.::...:|.   ..:.||.|..|.:|:.|.......|||||||:.|:||:|||:||.:|..
Zfish  1633 GENDQESEADLAGFKEVMQTIEEGDVDDMTKRRVYEIKEKPGALWHIYAAKDAEKIRELLRKVGE 1697

  Fly   720 EKGFRLEPDHDPIHDQNWYLDDKLRARLFKEYGVEGHPIVQCLGDAVFIPAGAPHQVQNLHNCIK 784
            |:|....|||||||||:||||..||.||::||||:|..|||.|||||||||||||||.||::|||
Zfish  1698 EQGQENPPDHDPIHDQSWYLDQTLRRRLYEEYGVQGWSIVQFLGDAVFIPAGAPHQVHNLYSCIK 1762

  Fly   785 VAEDFVSPENITHCYHLTHEFRRLSHSHTNHEDKLQIKNIIYHAIKDCCTIL 836
            .||||||||::.||:.||.|||.||::|||||||||:|||||||:||....|
Zfish  1763 AAEDFVSPEHVKHCFRLTQEFRHLSNTHTNHEDKLQVKNIIYHAVKDAVATL 1814

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kdm3	NP_788611.1	JmjC	605..657	CDD:214721	37/53 (70%)
		cupin_RmlC-like	694..789	CDD:477354	65/94 (69%)
kdm3b	XP_005173195.2	None