Protein Alignment Kdm3 and Kdm3

DIOPT Version :10

• Sequence 1: NP_788611.1
• Gene: Kdm3 / 41143
• FlyBaseID: FBgn0037703
• Length: 854
• Species: Drosophila melanogaster
• Sequence 2: XP_061497453.1
• Gene: Kdm3 / 1273280
• VectorBaseID: AGAMI1_003529
• Length: 2335
• Species: Anopheles gambiae
• Alignment Length: 1044
• Identity: 391/1044 - (37%)
• Similarity: 524/1044 - (50%)
• Gaps: 282/1044 - (27%)

  Fly    60 LKAEQRVQQEEESLGQV-PPL-TEEEQQRHDEFR--NSGSIFLQDLPCFKLQQAQPIAGSSPIPK 120
            |:.||.:.|:.:::.:. ||. |:..::|....|  .....|||:.||:|:        :|.:|:
Mosquito  1311 LEYEQLLYQKIQAMKRKNPPKDTDPNKRRRSNPRPKRPTEAFLQNGPCYKV--------ASRLPR 1367

  Fly   121 CRECRRRNLATTEGEPSSVSDVYCRFYEFRRLQFNENGELCVVGFPNPYSEPSPEDIAIWQPDKN 185
            ||||.|.  |......:|:  ::|||..||:|::|::|:|.|.||.:|..:....|.::|..:..
Mosquito  1368 CRECGRS--AAVRSRNASI--IFCRFIAFRKLRYNDSGQLEVYGFADPIWDAKEADTSLWSSNLQ 1428

  Fly   186 TPPTSGYMDIQVCRYILLHAGDQFCYIWHQEAEALSLHQNTDGTIAWKKAVKGTREICDVCDTTL 250
            ..|..  :.::..:::|...|.:||.::|||.||...|...|.|||||:||:|.||:||||.|||
Mosquito  1429 KVPAD--LSVEKSKFLLGQVGYKFCELFHQEKEAYYEHMAEDKTIAWKQAVQGVREMCDVCQTTL 1491

  Fly   251 FNYHWTCRKCGFGVCLDCVKDRKEGLRLRRAENAAQKGCDEYHWLLCSDPSGPQEHVLTELMLTQ 315
            ||:||.|..|||.||:||.|.||.|  :..|:::| |..|...|||||....|  |..|.|||||
Mosquito  1492 FNHHWVCSTCGFVVCIDCYKCRKNG--IITADSSA-KDKDANGWLLCSATKEP--HDQTRLMLTQ 1551

  Fly   316 IIAGDALNVLGRLLHEVRTLWQVPQVCGCLLSKQ------------------------------- 349
            ||....|..|.|.:|.:..|.::|..|.|.|:::
Mosquito  1552 IIPSKCLYTLVRQMHGICALLEIPLNCDCPLTREPPLRKIMDQLKFIYPLMPDEAGGALEFTGGE 1616

  Fly   350 -------------------AIEDAQSKE--------VIQDMIKESQLKQHTSYSSLASEQKVHQQ 387
                               .::..:::|        |.....:|.:.:|:...||.:.:::.::.
Mosquito  1617 VSVTIKQIEQMTMGGSNGKVVDGLKNEESDPYECRIVFMQQYRECREQQNAWPSSCSGQEEANEA 1681

  Fly   388 QRLDQ----------LHATKLEFAREL-------------------------------------- 404
            .:..|          :||....|...|
Mosquito  1682 AKEKQSYSFDGFEREIHAAGDHFDERLYKATAVSKAPVKAEHEQDGDKMLTDSPDDEGVVLGTNS 1746

  Fly   405 -----------------GVDYV---PGRV-------WTKETLGKDPIT------------TAFDN 430
                             ||..|   |.|:       .::|..|..|:.            ||.||
Mosquito  1747 NESFVTESETEHQGGGGGVPNVKQEPNRLVNNRTSNGSQEGSGNVPLKTECAVPAANGNGTANDN 1811

  Fly   431 ------------------------------------------------------LKH-------- 433
                                                                  .:|
Mosquito  1812 GTKEVPQTLPVPYSEEDRFKPSPTVDEKTVTMIIKQVVKTDKSIFPLLQPHMVSTRHQLNDFVEC 1876

  Fly   434 -------------------------------------INFLRKGLAGLRRF--LPPRTMTFAYST 459
                                                 :::.|....|..|:  ...|.|....|.
Mosquito  1877 VSIQRERAKQFVAEFLDEFIFLKGQNGSDDLVNDRATVDYNRSMKEGAARYRNKSERRMNLVQSK 1941

  Fly   460 QLAPGVPHEFLCDGRLLRLTDAMHPDNRVLFQEVWKCGQPVMISEVARSLNLDLWHPQAFCRDFG 524
            .|.|.|.|::||:||||||.|.:...|..:|.|.|:.|||||:|.|:..:|:|||.|.:|.||||
Mosquito  1942 TLYPDVAHDWLCNGRLLRLLDPLDVHNYRVFHEQWERGQPVMVSAVSSKMNMDLWLPGSFGRDFG 2006

  Fly   525 DKPNDLINCLNGNLVPNQPMRHFWEGFQCMTKRLPDAYGKPMLLKLKDWPPGDDFAEILPTRFAD 589
            |:.|||||||||.:|...|||.|||||:.:::||.|...:||:||||||||||||||::||||.|
Mosquito  2007 DQVNDLINCLNGKIVRGHPMRVFWEGFEELSERLLDERERPMMLKLKDWPPGDDFAEMMPTRFYD 2071

  Fly   590 LMKGLPMPEYTLRTGNLNIASCLPKMFVPPDLGPKMYNAYGSALHPDKGTTNLHLDISDAVNIMV 654
            |||.||:.|||.|.|.||:||.|...||.||||||||:||||||||.|||||||||||||||:||
Mosquito  2072 LMKSLPLAEYTRREGRLNLASRLSSFFVRPDLGPKMYSAYGSALHPTKGTTNLHLDISDAVNVMV 2136

  Fly   655 YVGIPQDGDTRPQMAATQKAIEI---GGCDYITRARCQSPDVLPGALWHIFPARDADKIRDLLNR 716
            |||:|:|   .|.....:|.:|:   ..|||:||.|.:....||||||||:.|:||||||.||||
Mosquito  2137 YVGVPRD---VPSARYNEKIVELIDSEDCDYLTRQRVRERKELPGALWHIYHAQDADKIRALLNR 2198

  Fly   717 VTLEKGFRLEPDHDPIHDQNWYLDDKLRARLFKEYGVEGHPIVQCLGDAVFIPAGAPHQVQNLHN 781
            :.||:|..::|:|||||||.||||..||.||.:||.|||:.||||.|||:||||||||||:||||
Mosquito  2199 IELERGGTIKPNHDPIHDQKWYLDRNLRKRLQQEYHVEGYAIVQCAGDAIFIPAGAPHQVRNLHN 2263

  Fly   782 CIKVAEDFVSPENITHCYHLTHEFRRLSHSHTNHEDKLQIKNIIYHAIKDCCTILT-------RA 839
            |||||||||||||::||..||:|||.||.:|:||||||||||||||.:||..:.:|       |.
Mosquito  2264 CIKVAEDFVSPENVSHCLKLTNEFRHLSGTHSNHEDKLQIKNIIYHTVKDAVSCITNPLIRMARG 2328

  Fly   840 VDER 843
            .|||
Mosquito  2329 EDER 2332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kdm3	NP_788611.1	JmjC	605..657	CDD:214721	41/51 (80%)
		cupin_RmlC-like	694..789	CDD:477354	70/94 (74%)
Kdm3	XP_061497453.1	None