Protein Alignment Kdm3 and jmjd1c

DIOPT Version :10

• Sequence 1: NP_788611.1
• Gene: Kdm3 / 41143
• FlyBaseID: FBgn0037703
• Length: 854
• Species: Drosophila melanogaster
• Sequence 2: XP_031761210.1
• Gene: jmjd1c / 100487525
• XenbaseID: XB-GENE-1008867
• Length: 2528
• Species: Xenopus tropicalis
• Alignment Length: 985
• Identity: 321/985 - (32%)
• Similarity: 457/985 - (46%)
• Gaps: 228/985 - (23%)

  Fly    12 TRTSRKRTISSTSFS-----ISTRTDPKSIIEIHIFNDSLPIKRACCEVENPTLKAEQRVQQ--- 68
            ||...|||..|.|.|     ..:|:.|:             :||.    ..||.|.:|...|
 Frog  1603 TRRRVKRTYESGSESEDSDESESRSGPR-------------LKRQ----PKPTYKKKQNDMQRRK 1650

  Fly    69 -----EEE---------------------SLGQ--VPPLTEEEQQRHDEFRNSGSIFLQDLPCFK 105
                 |||                     |.|.  :|....::.::..:.:.:|..||||..|.:
 Frog  1651 GDTDKEEECKPNGILSRSAKEKSKLKLQSSSGNTGIPRSVLKDWRKVKKLKQTGESFLQDDSCCE 1715

  Fly   106 LQQAQPIAGSSPIPKCRECRRRNLATTEGEPSSVSDVYCRFYEFRRLQFNENGELCVVGFPNPYS 170
            :        ...:.||||||.  :.|.:||.|:.|.|:||||.||||.|::||.:.:.||.:| .
 Frog  1716 I--------GPNLQKCRECRL--IRTKKGEESTHSPVFCRFYYFRRLSFSKNGVVRIDGFSSP-D 1769

  Fly   171 EPSPEDIAIW-----QPDKNTPPTSGYMDIQVCRYILLHAGDQFCYIWHQEAEALSLHQNTDGTI 230
            :...|.:::|     :.|:        :|:...:|||.:.||:||.:...|..|:|..:. |..|
 Frog  1770 QYDDEALSLWSHEHYEDDE--------LDLDTIKYILAYIGDKFCQLGTSEKAAVSWVKK-DAKI 1825

  Fly   231 AWKKAVKGTREICDVCDTTLFNYHWTCRKCGFGVCLDCVKDRKEGLRLRRAENAAQKGCDEYHWL 295
            |||:||:|.||:||.|:.||||.||.|:||||.|||||.|.:         |....:..:.|.|:
 Frog  1826 AWKRAVRGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAK---------ERKISRDKELYTWM 1881

  Fly   296 LCSDPSGPQEHVLTELMLTQIIAGDALNVLGRLLHEVRTLWQVPQVCGCL--------------- 345
            .|..   .|.|....||.||||....|..|...:|.:|..:.:...|.|.
 Frog  1882 KCVK---GQPHDYKHLMPTQIIPSSVLTDLLEAMHHLRDRFGIKSHCHCASKPCPPAPKYPAMNG 1943

  Fly   346 -------------------------LSKQAIEDAQSKEVIQDMIKESQLKQHTSYSSL-----AS 380
                                     .|.|..|...:.....|...:|:|....|:|||     .:
 Frog  1944 VSQVLQNVLNHSNKISLCLPESPHQSSPQKPETNGNASPGSDSSTDSKLTSSESHSSLHWLADLA 2008

  Fly   381 EQKVHQQQRLDQLHATKLEFARELGVDYVPGRVWTKE-------------------------TLG 420
            |||..::::.::               ..||....||                         ||
 Frog  2009 EQKSREEKKENK---------------ECPGGKHIKEERDQEVSETVNCKSSPTSHSNEQGSTL- 2057

  Fly   421 KDPITTAFDNLK---------------HINFLRKGLAGLRRFLP-----------PRTMTFAYST 459
            :|.:||....|:               ..|...||...:...|.           |.|.|.....
 Frog  2058 RDLLTTTAGKLRLGSTDAGIAFAPVYSASNPCNKGGRSMPNILDDIIASVVENKIPATKTPKPIV 2122

  Fly   460 QLAP-----------------GVPHEFLCDGRLLRLTDAMHPDNRVLFQEVWKCGQPVMISEVAR 507
            |..|                 .:||.::||..:|.|.|..|..|..:|||.||.|:.|::|...:
 Frog  2123 QSEPKEEIVEVPLEEPETEHQEIPHSWICDRHILWLKDHKHSRNWKMFQECWKQGKTVVVSGTHK 2187

  Fly   508 SLNLDLWHPQAFCRDFGDKPNDLINCLNGNLVPNQPMRHFWEGFQCMTKRLPDAYGKPMLLKLKD 572
            .:|.:||..:|...||||...||:||..| :|.:..:..|||||:.::||.....|:.:||||||
 Frog  2188 RMNANLWKLEAISSDFGDHQGDLLNCKEG-IVSSGNVTDFWEGFEDVSKRQKVKNGETVLLKLKD 2251

  Fly   573 WPPGDDFAEILPTRFADLMKGLPMPEYTLRTGNLNIASCLPKMFVPPDLGPKMYNAYG--SALHP 635
            .|.|:||..::..|..:..|.||:|||....|..|:||.:|..||.|||||:|.:|||  :....
 Frog  2252 QPSGEDFKNMMLARHEEFFKMLPVPEYCNPDGKFNLASHMPSFFVRPDLGPRMCSAYGVIATKDQ 2316

  Fly   636 DKGTTNLHLDISDAVNIMVYVGIPQDGDTRPQMAATQKAIEIGGCDYITRARCQSPDVLPGALWH 700
            |.||||||:::||.|||:||||..:.....|:....:| .|....|...|.|.:....:||:|||
 Frog  2317 DTGTTNLHIEVSDLVNILVYVGAAKGLGVMPKSGVLKK-FEEEELDEHLRKRLKDSGEVPGSLWH 2380

  Fly   701 IFPARDADKIRDLLNRVTLEKGFRLEPDHDPIHDQNWYLDDKLRARLFKEYGVEGHPIVQCLGDA 765
            |:..|||||||:.|::...|:...:.||||||.||||||..|||..|.::|||:.:.:||.||||
 Frog  2381 IYETRDADKIREFLHKAAKEQCLEILPDHDPIRDQNWYLSKKLRQSLLEDYGVKSYTLVQFLGDA 2445

  Fly   766 VFIPAGAPHQVQNLHNCIKVAEDFVSPENITHCYHLTHEFRRLSHSHTNHEDKLQIKNIIYHAIK 830
            |.:||||.:||||.|:||:|.:||||||::...:|||.|.|. |....|::||||:|||:||::|
 Frog  2446 VILPAGAIYQVQNFHSCIQVTQDFVSPEHLVQSFHLTQELRH-SKEEINYDDKLQVKNILYHSVK 2509

  Fly   831 DCCTILTRAV 840
            :    :.||:
 Frog  2510 E----MVRAL 2515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kdm3	NP_788611.1	JmjC	605..657	CDD:214721	29/53 (55%)
		cupin_RmlC-like	694..789	CDD:477354	53/94 (56%)
jmjd1c	XP_031761210.1	DUF5585	1082..>1510	CDD:465521
		KLF1_2_4_N	<1118..1252	CDD:425360
		JmjC	2266..2338	CDD:214721	36/71 (51%)
		cupin_RmlC-like	<2379..2469	CDD:477354	50/89 (56%)