DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ras85D and CG8641

DIOPT Version :9

Sequence 1:	NP_476699.1	Gene:	Ras85D / 41140	FlyBaseID:	FBgn0003205	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_001261494.1	Gene:	CG8641 / 38771	FlyBaseID:	FBgn0035733	Length:	434	Species:	Drosophila melanogaster

Alignment Length:	174	Identity:	61/174 - (35%)
Similarity:	93/174 - (53%)	Gaps:	21/174 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 YKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMR 68
            |:||::|:...|||::..:.:.|.|.:.|.||||:.:||...|..|...||||||:|...:.|||
  Fly   167 YRLVMLGSSRAGKSSIVARFLGNRFEEAYTPTIEEFHRKLYRIRNEVFQLDILDTSGYHPFPAMR 231

  Fly    69 DQYMRTGEGFLLVFAVNSAKSFEDIGTYREQIKRVKDA-------------EEVPMVLVGNKCDL 120
            .....||:.|:|||:::|.:|||::...||.|...|.|             .::||:|.|||||.
  Fly   232 RLSFLTGDLFILVFSMDSRESFEEVVRLRENILETKWAALNPGSGFKKKSLPKIPMILAGNKCDR 296

  Fly   121 ASWNVNNEQAREV-----AKQYGIPYIETSAKTRMGVDDAFYTL 159
               :....|..||     .:.....::|.||:....:||.|::|
  Fly   297 ---DFKTVQVDEVMGYIAGQDNCCTFVECSARQNYRIDDLFHSL 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ras85D	NP_476699.1	H_N_K_Ras_like	3..164	CDD:133338	61/174 (35%)
CG8641	NP_001261494.1	Rhes_like	167..434	CDD:133343	61/174 (35%)
CG8641	NP_001261494.1	RAS	167..338	CDD:214541	61/174 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453055
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740