DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ras85D and kappaB-Ras

DIOPT Version :9

Sequence 1:	NP_476699.1	Gene:	Ras85D / 41140	FlyBaseID:	FBgn0003205	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_001137613.1	Gene:	kappaB-Ras / 35667	FlyBaseID:	FBgn0040513	Length:	201	Species:	Drosophila melanogaster

Alignment Length:	168	Identity:	52/168 - (30%)
Similarity:	80/168 - (47%)	Gaps:	18/168 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KLVVVGAGGVGKSALTIQLIQNHFVDEYD--PTIEDSYRKQVVI--DGETCLLDILDTAG-QEEY 64
            |::|.|..||||:||..||:..|...|.:  |||||.|...|..  .|....|.|.|||| |.|.
  Fly    11 KVLVCGMKGVGKTALIEQLVYGHVNPETELHPTIEDIYVASVDTGRGGARETLRIYDTAGLQGEQ 75

  Fly    65 SAMRDQYMRTGEGFLLVFAVNSAKSFEDIGTYREQIKRVKDAEEVPMVLVGNKCDLASWN----- 124
            ..:...|::..:.|:||:.....:|.:.:...:..|::.|:.:|:|:|::.|....|:.|
  Fly    76 QQLPRHYLQFPDAFVLVYDPMDPRSLDMLADIKADIEKHKEKKEIPVVVLANVRARAAPNPVEKV 140

  Fly   125 ---VNNEQAREVAKQYGIPYIETSAKTRMGVDDAFYTL 159
               .|....||..|.|.:     :|..|..:.:.|.||
  Fly   141 MDRANIWCQRERIKHYTV-----NAMERPSLYEPFTTL 173

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ras85D	NP_476699.1	H_N_K_Ras_like	3..164	CDD:133338	52/168 (31%)
kappaB-Ras	NP_001137613.1	Ras	11..173	CDD:278499	50/166 (30%)
kappaB-Ras	NP_001137613.1	Ras_like_GTPase	13..174	CDD:206648	51/166 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453066
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840