DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ras85D and Rras

DIOPT Version :9

Sequence 1:	NP_476699.1	Gene:	Ras85D / 41140	FlyBaseID:	FBgn0003205	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_033127.1	Gene:	Rras / 20130	MGIID:	98179	Length:	218	Species:	Mus musculus

Alignment Length:	168	Identity:	95/168 - (56%)
Similarity:	120/168 - (71%)	Gaps:	1/168 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 YKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMR 68
            :||||||.|||||||||||.||::||.:|||||||||.|...:||....|||||||||||:.|||
Mouse    30 HKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICTVDGIPARLDILDTAGQEEFGAMR 94

  Fly    69 DQYMRTGEGFLLVFAVNSAKSFEDIGTYREQIKRVKDAEEVPMVLVGNKCDLASW-NVNNEQARE 132
            :||||.|.|||||||:|..:||.::|....||.||||.::.|:||||||.||.:. .|...:|..
Mouse    95 EQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADLENQRQVLRSEASS 159

  Fly   133 VAKQYGIPYIETSAKTRMGVDDAFYTLVREIRKDKDNK 170
            .:..:.:.|.|.|||.|:.||:||..|||.:||.::.:
Mouse   160 FSASHHMTYFEASAKLRLNVDEAFEQLVRAVRKYQEQE 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ras85D	NP_476699.1	H_N_K_Ras_like	3..164	CDD:133338	93/160 (58%)
Rras	NP_033127.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..30		95/168 (57%)
		M_R_Ras_like	28..191	CDD:133345	93/160 (58%)
		Effector region	58..66		7/7 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1259506at2759
OrthoFinder	1	1.000	-	-		FOG0000092
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1068
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850