Protein Alignment Ras85D and Hras

DIOPT Version :9

• Sequence 1: NP_476699.1
• Gene: Ras85D / 41140
• FlyBaseID: FBgn0003205
• Length: 189
• Species: Drosophila melanogaster
• Sequence 2: NP_001123915.1
• Gene: Hras / 15461
• MGIID: 96224
• Length: 189
• Species: Mus musculus
• Alignment Length: 191
• Identity: 149/191 - (78%)
• Similarity: 164/191 - (85%)
• Gaps: 10/191 - (5%)

  Fly     1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYS 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse     1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYS 65

  Fly    66 AMRDQYMRTGEGFLLVFAVNSAKSFEDIGTYREQIKRVKDAEEVPMVLVGNKCDLASWNVNNEQA 130
            ||||||||||||||.|||:|:.||||||..||||||||||:::|||||||||||||:..|.:.||
Mouse    66 AMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQA 130

  Fly   131 REVAKQYGIPYIETSAKTRMGVDDAFYTLVREIRKDKDNKGRRGRKMNKPNRR----FKCK 187
            :::|:.|||||||||||||.||:|||||||||||:.|      .||:|.|:..    ..||
Mouse   131 QDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHK------LRKLNPPDESGPGCMSCK 185

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ras85D	NP_476699.1	H_N_K_Ras_like	3..164	CDD:133338	138/160 (86%)
Hras	NP_001123915.1	H_N_K_Ras_like	3..164	CDD:133338	138/160 (86%)
		Effector region	32..40		7/7 (100%)
		Hypervariable region	166..185		5/24 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837056
Domainoid	1	1.000	280	1.000	Domainoid score	I1666
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I2757
Isobase	1	0.950	-	0	Normalized mean entropy	S22
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1259506at2759
OrthoFinder	1	1.000	-	-		FOG0000092
OrthoInspector	1	1.000	-	-		otm42700
orthoMCL	1	0.900	-	-		OOG6_100217
Panther	1	1.100	-	-	LDO	PTHR24070
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1068
SonicParanoid	1	1.000	-	-		X934
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.780