Protein Alignment rump and HRB1

DIOPT Version :10

• Sequence 1: NP_649899.1
• Gene: rump / 41138
• FlyBaseID: FBgn0267790
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_014394.2
• Gene: HRB1 / 855728
• SGDID: S000004949
• Length: 454
• Species: Saccharomyces cerevisiae
• Alignment Length: 569
• Identity: 117/569 - (20%)
• Similarity: 194/569 - (34%)
• Gaps: 172/569 - (30%)

  Fly   112 QKALEKMNRYEVNGRELV---VKEDHGEQRDQYGRIVRDGGGGGGGGGGVQGGNGGNNGGGGGGG 173
            ::..|..||.....|..|   :.:|||.:||.:  :.|..|...|.........|..:.|...||
Yeast     5 ERGSENNNRSRSRSRSPVRRRMSDDHGYERDNH--LSRRSGNYNGRRKFADTYRGSRDRGEYRGG 67

  Fly   174 RDHMDDRDR-GFSRRD--------DDRLSGRN---NFNMMSNDYNNS--SNYNL--------YGL 216
            |:..|.|:| .|:.||        |||..||:   .:....:||..|  |.:|.        :|.
Yeast    68 RERSDYRERERFNNRDNPRSRDRYDDRRRGRDVTGRYGNRRDDYPRSFRSRHNTRDDSRRGGFGS 132

  Fly   217 SASFLESLGISGPL-----------------HNKVFVANLDYKVDNKKLKQVFKLAGKVQSVDLS 264
            |.    :.|..|||                 .|.:||.||.|....:.|.:.|...|||...|:
Yeast   133 SG----ARGDYGPLLARELDSTYEEKVNRNYSNSIFVGNLTYDSTPEDLTEFFSQIGKVVRADI- 192

  Fly   265 LDKEGNSRGFAVIEYDHPVEAVQAISMLDRQMLFDRRMTVRLDRIPDKNEGIKLPEGLGGVGIGL 329
            :...|:.||...:|:.:..:..:||...|.....||::.||.|..|..| .||..:.|
Yeast   193 ITSRGHHRGMGTVEFTNSDDVDRAIRQYDGAFFMDRKIFVRQDNPPPSN-NIKERKAL------- 249

  Fly   330 GPNGEPLRDVAHNLPNGGQSQGQLLGNAQQGSQLGSVGSQPNSSAVSNATTNLLNNLTGVMFGNH 394
                               .:|:|..|.:                                  .|
Yeast   250 -------------------DRGELRHNRK----------------------------------TH 261

  Fly   395 AAVQPSPVAPVQKPSLGNNTGSGGLNLNNLNPSILAAVVGNLGNQGGNLSNPLLSSSLSNLGLNL 459
            ..:                       :.||..|:....:.::..:.||:::
Yeast   262 EVI-----------------------VKNLPASVNWQALKDIFKECGNVAH-------------- 289

  Fly   460 GNSGNDDNLPPSNVGLSNNYSSGGTGGGNSYSSGNNYSGGGGSSNLGYNAYSSSGGMGGGNGGVG 524
                       ::|.|..:..|.|:|..:.|...:.:     .:...||.||..|.:........
Yeast   290 -----------ADVELDGDGVSTGSGTVSFYDIKDLH-----RAIEKYNGYSIEGNVLDVKSKES 338

  Fly   525 VDGNDYNTGNPLDVYGGGSNVG-NSNVGSANAVGASRKSDTIIIKNVPITCTWQTLRDKFREIGD 588
            |  ::::.|:.:|:....|.|. .:...:.|.||...::..|...|:|.:.....|.|.|..||.
Yeast   339 V--HNHSDGDDVDIPMDDSPVNEEARKFTENVVGGGERNRLIYCSNLPFSTAKSDLYDLFETIGK 401

  Fly   589 VKFAEIRGNDVG------VVRFFKERDAELAIALMDGSRLDGRNIKVTY 631
            |..||:|.:..|      ||.:....||::.|..::.....|.::.::|
Yeast   402 VNNAELRYDSKGAPTGIAVVEYDNVDDADVCIERLNNYNYGGCDLDISY 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rump	NP_649899.1	PABP-1234	48..435	CDD:130689	76/364 (21%)
		RRM1_hnRNPM_like	58..133	CDD:409819	5/23 (22%)
		RRM2_hnRNPM_like	234..307	CDD:409820	22/72 (31%)
		RRM_SF	565..629	CDD:473069	19/69 (28%)
HRB1	NP_014394.2	PRK12678	<29..>85	CDD:237171	19/57 (33%)
		RRM1_HRB1_GBP2	160..236	CDD:410184	23/76 (30%)
		RRM2_HRB1_GBP2	262..334	CDD:410185	16/124 (13%)
		RRM3_HRB1_GBP2	374..452	CDD:410186	20/77 (26%)