DRSC/TRiP Functional Genomics Resources

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Protein Alignment rump and Cstf2t

DIOPT Version :9

Sequence 1:NP_649899.1 Gene:rump / 41138 FlyBaseID:FBgn0267790 Length:632 Species:Drosophila melanogaster
Sequence 2:NP_112539.2 Gene:Cstf2t / 83410 MGIID:1932622 Length:632 Species:Mus musculus


Alignment Length:611 Identity:122/611 - (19%)
Similarity:203/611 - (33%) Gaps:207/611 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 VAARDRSRERRNCRVYISNIPYDYRWQDLKDLFRRIVGSIEYVQLFFD-ESGKARGCGIVEFKDP 108
            :|.||.:.:|....|::.||||:...:.|||:|.. |||:...:|.:| |:||.:|.|..|::|.
Mouse     4 LAVRDPAMDRSLRSVFVGNIPYEATEEQLKDIFSE-VGSVVSFRLVYDRETGKPKGYGFCEYQDQ 67

  Fly   109 ENVQKALEKMNRYEVNGRELVVKEDHGEQRDQYGRIVRDGGGGGGGGGGVQGGNGGNNGGGGGGG 173
            |....|:..:|..|.:||.|                                             
Mouse    68 ETALSAMRNLNGREFSGRAL--------------------------------------------- 87

  Fly   174 RDHMDDRDRGFSRRDDDRLSGRNNFNMMSNDYNNSSNYNLYGLSASFLESLGISGPLHNKVFVAN 238
                         |.|:..|.:|.                     ..|:|||.:.|:.:..:...
Mouse    88 -------------RVDNAASEKNK---------------------EELKSLGPAAPIIDSPYGDP 118

  Fly   239 LDYK---------VDNKKLKQVFKLAGKVQSVDLSLDKEGNSR-------GFAVIEYDHPVEAVQ 287
            :|.:         |.:...:|:|:|..:::....:..:|..:.       .:|::      :|..
Mouse   119 IDPEDAPESITRAVASLPPEQMFELMKQMKLCVQNSHQEARNMLLQNPQLAYALL------QAQV 177

  Fly   288 AISMLDRQM---LFDRRMTVRLDRIPDKNEGIKLPEGLGGVGIGLGPNGEPLRDVAHNLPNGGQS 349
            .:.::|.::   :..|::.| ...||.|::.:..| |.||.|.. ||.|          |..|.:
Mouse   178 VMRIMDPEIALKILHRKIHV-TPLIPGKSQPVSGP-GPGGPGPS-GPGG----------PGPGPA 229

  Fly   350 QGQLLGNAQQGSQLGSVGSQPN---SSAVSNATTNLLNNLTGVMFGNHAAVQPSPV-APVQKPSL 410
            .|...|.....:|......||.   ...|.:....:..::.|      ....|.|: |.|..|..
Mouse   230 PGLCPGPNVMLNQQNPPAPQPQHLPRRPVKDIPPLMQTSIQG------GIPAPGPIPAAVPGPGP 288

  Fly   411 GNNTGSGGLNLNNLNPSILAAVVGNLGNQGGNLS----------NPLLSSSLSNLGLNLGNSGND 465
            |:.|..|.     :.|.:...|||.:..:.|.:.          .|:.|..:...|| ||::.||
Mouse   289 GSLTPGGA-----MQPQVGMPVVGPVPLERGQMQISDPRPPMPRGPMPSGGIPPRGL-LGDAPND 347

  Fly   466 DNLPPSNVGLSNNYSSGGTGGGNSYSSGNNYSGGG-------------GSSNLGYNAYSSSGG-- 515
            ..                  ||...|........|             |..|.|..::...||  
Mouse   348 PR------------------GGTLLSVTGEVEPRGYMGPPHQGPPMHHGHDNRGPASHDMRGGPL 394

  Fly   516 ------MGGGNGGVGVDGNDYNTGNPLDVYGGGSNVGNSNVGSANAV----GASRKSDTIIIKNV 570
                  :.|...|..:|    ..|.|:|..||..:.|.........|    |..|:.:       
Mouse   395 AADPRMLIGEPRGPMID----QRGLPMDGRGGRESRGMETRPMETEVLEPRGMERRME------- 448

  Fly   571 PITCTWQTLRDKFREIGDVKFAEIRG 596
              ||..:|     |.: |.:..|:||
Mouse   449 --TCAMET-----RGM-DARGLEMRG 466

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rumpNP_649899.1 PABP-1234 48..435 CDD:130689 82/410 (20%)
RRM1_hnRNPM_like 58..133 CDD:240831 28/75 (37%)
RRM2_hnRNPM_like 234..307 CDD:240832 11/91 (12%)
RRM <543..>631 CDD:223796 12/58 (21%)
RRM_SF 565..630 CDD:302621 8/32 (25%)
Cstf2tNP_112539.2 RRM <16..>109 CDD:223796 36/172 (21%)
RRM_CSTF2_CSTF2T 18..92 CDD:241115 30/132 (23%)
CSTF2_hinge 113..191 CDD:291025 9/83 (11%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 201..296 27/112 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 365..433 14/71 (20%)
8 X 5 AA tandem repeats of M-E-T-R-[AG] 428..466 9/52 (17%)
12 X 5 AA tandem repeats of G-[AT]-G-[MI]-Q 508..565
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 519..590
CSTF_C 588..628 CDD:291002
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0724
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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