DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rump and Srsf1

DIOPT Version :9

Sequence 1:	NP_649899.1	Gene:	rump / 41138	FlyBaseID:	FBgn0267790	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_001103022.1	Gene:	Srsf1 / 689890	RGDID:	1587490	Length:	248	Species:	Rattus norvegicus

Alignment Length:	256	Identity:	66/256 - (25%)
Similarity:	95/256 - (37%)	Gaps:	86/256 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 GGGVAARDRSRERRNCRVYISNIPYDYRWQDLKDLFRRIVGSIEYVQLFFDESGKARGCG----I 102
            ||||......  ..:||:|:.|:|.|.|.:|::|:|.: .|:|..:.|      |.|..|    .
  Rat     3 GGGVIRGPAG--NNDCRIYVGNLPPDIRTKDIEDVFYK-YGAIRDIDL------KNRRGGPPFAF 58

  Fly   103 VEFKDPENVQKALEKMNRYEVNGRELVVKEDHGEQRDQYGRIVRDGGGGGGGGGGVQGGNGGNNG 167
            |||:||.:.:.|:...:.|:.:|..|.|:            ..|.|.|.|.||||         |
  Rat    59 VEFEDPRDAEDAVYGRDGYDYDGYRLRVE------------FPRSGRGTGRGGGG---------G 102

  Fly   168 GGGGGGRDHMDDRDRGFSRRDDDRLSGRNNFNMMSNDYNNSSNYNLYGLSASFLESLGISGPLHN 232
            ||||..|                   ||                  ||..:...|         |
  Rat   103 GGGGAPR-------------------GR------------------YGPPSRRSE---------N 121

  Fly   233 KVFVANLDYKVDNKKLKQVFKLAGKVQSVDLSLDKEGNSRGFAVIEYDHPVEAVQAISMLD 293
            :|.|:.|......:.||...:.||.|...|:..|      |..|:|:....:...|:..||
  Rat   122 RVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRD------GTGVVEFVRKEDMTYAVRKLD 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rump	NP_649899.1	PABP-1234	48..435	CDD:130689	62/250 (25%)
		RRM1_hnRNPM_like	58..133	CDD:240831	25/78 (32%)
		RRM2_hnRNPM_like	234..307	CDD:240832	16/60 (27%)
		RRM	<543..>631	CDD:223796
		RRM_SF	565..630	CDD:302621
Srsf1	NP_001103022.1	RRM1_SRSF1	12..90	CDD:410010	26/98 (27%)
Srsf1	NP_001103022.1	RRM2_SRSF1	113..196	CDD:410160	19/79 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900