Protein Alignment rump and Myef2

DIOPT Version :10

• Sequence 1: NP_649899.1
• Gene: rump / 41138
• FlyBaseID: FBgn0267790
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001013223.2
• Gene: Myef2 / 679712
• RGDID: 1306547
• Length: 591
• Species: Rattus norvegicus
• Alignment Length: 668
• Identity: 210/668 - (31%)
• Similarity: 306/668 - (45%)
• Gaps: 164/668 - (24%)

  Fly     1 MSMDASNSVESREKERDRRGRG-ARGSRFTDADGNGN-GAGSQGGGVAARDRSRERRNCRVYISN 63
            :.|:...||:..:.:...:..| .:.:||.....:.| |.|.:.|         ..|| ||:|||
  Rat    43 VKMENDESVKEEKSDLKEKSTGNKKANRFHPYSKDKNSGTGEKKG---------PNRN-RVFISN 97

  Fly    64 IPYDYRWQDLKDLFRRIVGSIEYVQLFFDESGKARGCGIVEFKDPENVQKALEKMNRYEVNGREL 128
            ||||.:||.:|||.|..||.:.||:||.|..||:||||:|||||.|.|:||||.||:|:::||.|
  Rat    98 IPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPL 162

  Fly   129 VVKED-HGE------QRDQYGRIVRDGGGGGGGGGGVQGGNGGNNGGGGGGGRDHMDDRDRGFSR 186
            .:||| .||      ||.               |...||.:..:.|.|
  Rat   163 NIKEDPDGENARRALQRT---------------GTSFQGSHASDVGSG----------------- 195

  Fly   187 RDDDRLSGRNNFNMMSNDYNNSSNYNLYGLSASFLESLGISGPLHNKVFVANLDYKVDNKKLKQV 251
                      ..|:..:..||.:      :....:.:|. :|.|.:.:||||||:||..||||:|
  Rat   196 ----------LVNLPPSIVNNPN------IPPEVINNLQ-AGRLGSTIFVANLDFKVGWKKLKEV 243

  Fly   252 FKLAGKVQSVDLSLDKEGNSRGFAVIEYDHPVEAVQAISMLDRQMLFDRRMTVRLD--RIPDK-- 312
            |.:||.|:..|:..||:|.|||...:.::..:||||||||.:.|.||||.|.|::|  .:|.:
  Rat   244 FSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEDY 308

  Fly   313 ----NEGIKLPEGLGGVGIGLGPNGEPLRDVAHNLPNGGQSQGQLLGNAQQGSQLGSVGSQPNSS 373
                ::..:||.||||:|:||||.|:|:                      ..|||
  Rat   309 RSHDSKTSQLPRGLGGIGMGLGPGGQPI----------------------SASQL---------- 341

  Fly   374 AVSNATTNLLNNLTGVMFGNHAAVQPSPVAPVQKPSLGN-NTGSGGLNLNNLNPSILAAVVGNLG 437
                       |:|||| ||   :.||.:. :..|..|. |...||:....|......|..|.:|
  Rat   342 -----------NITGVM-GN---LGPSGMG-MDGPGFGGVNRIGGGVGFGGLEAMNSMAGFGGVG 390

  Fly   438 NQGGNLSNPLLSSSLSNLGLNLGNSGNDDNLPPSNVGLSNNYSSGGTGGGNSYSSGNNYSGGGGS 502
            .. |.|....::||:..      :.|..|      :|||..:.......|::...|  ::|..|:
  Rat   391 RM-GELYRGAMTSSMER------DFGRGD------IGLSRGFGDSFGRLGSAMIGG--FAGRIGA 440

  Fly   503 SNLGYNAYSSSGGMGG-----GNGGVGVD--GNDYNTGNP---------LDVYGGGSNVGNSNVG 551
            ||:|......||.|.|     |..|:|:|  .:.::...|         :||..|..: |....|
  Rat   441 SNMGPVGTGISGSMSGMSTVTGGMGMGLDRMSSSFDRMGPGIGAILERSIDVDRGFLS-GPMGSG 504

  Fly   552 SANAVGASRKSDTIIIKNVPITCTWQTLRDKFREIGDVKFAEI-----RGNDVGVVRFFKERDAE 611
            ..:.:|:  |.:.|.::|:|...|||.|::||.:.|.|.||||     :....|.|||.....||
  Rat   505 MRDRLGS--KGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFESPESAE 567

  Fly   612 LAIALMDGSRLDGRNIKV 629
            .|..:|:|.::.||.|.|
  Rat   568 KACRIMNGIKISGREIDV 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rump	NP_649899.1	PABP-1234	48..435	CDD:130689	138/402 (34%)
		RRM1_hnRNPM_like	58..133	CDD:409819	46/74 (62%)
		RRM2_hnRNPM_like	234..307	CDD:409820	39/72 (54%)
		RRM_SF	565..629	CDD:473069	27/68 (40%)
Myef2	NP_001013223.2	RRM1_MYEF2	92..167	CDD:410059	46/74 (62%)
		PABP-1234	115..>587	CDD:130689	183/586 (31%)
		RRM2_MYEF2	224..299	CDD:410061	39/74 (53%)
		RRM3_MYEF2	515..591	CDD:410063	28/71 (39%)