Protein Alignment rump and SNRNP70

DIOPT Version :10

• Sequence 1: NP_649899.1
• Gene: rump / 41138
• FlyBaseID: FBgn0267790
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_003080.2
• Gene: SNRNP70 / 6625
• HGNCID: 11150
• Length: 437
• Species: Homo sapiens
• Alignment Length: 200
• Identity: 51/200 - (25%)
• Similarity: 86/200 - (43%)
• Gaps: 32/200 - (16%)

  Fly    10 ESREK--ERDRRGRGARGSRFTDAD----GNGNGAGSQGGGVAARDRSRERRNCRVYISNIPYDY 68
            |:||:  ||.||.:..|..:..:.:    ...|...:||.....           ::::.:.||.
Human    61 ETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKT-----------LFVARVNYDT 114

  Fly    69 RWQDLKDLFRRIVGSIEYVQLFFDE-SGKARGCGIVEFKDPENVQKALEKMNRYEVNGRELVVKE 132
            ....|:..| .:.|.|:.:.:.:.: |||.||...:|::...::..|.:..:..:::||.::|..
Human   115 TESKLRREF-EVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDV 178

  Fly   133 DHGEQRDQYG-RIVRDGGGGGG---GGGGVQGGNGGNNGGG------GGGGRDHMD-DRDRGFSR 186
            :.|  |...| |..|.|||.||   ||..|...:.|.:...      |.....|.| ||||...|
Human   179 ERG--RTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERER 241

  Fly   187 RDDDR 191
            |:..|
Human   242 RERSR 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rump	NP_649899.1	PABP-1234	48..435	CDD:130689	39/155 (25%)
		RRM1_hnRNPM_like	58..133	CDD:409819	16/75 (21%)
		RRM2_hnRNPM_like	234..307	CDD:409820
		RRM_SF	565..629	CDD:473069
SNRNP70	NP_003080.2	U1snRNP70_N	3..94	CDD:432406	8/32 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	48..79		8/17 (47%)
		Required for interaction with U1 RNA. /evidence=ECO:0000269|PubMed:2467746	92..202		29/123 (24%)
		RRM_snRNP70	102..187	CDD:409682	18/98 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	187..437		20/59 (34%)