DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rump and SRSF4

DIOPT Version :9

Sequence 1:	NP_649899.1	Gene:	rump / 41138	FlyBaseID:	FBgn0267790	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_005617.2	Gene:	SRSF4 / 6429	HGNCID:	10786	Length:	494	Species:	Homo sapiens

Alignment Length:	201	Identity:	52/201 - (25%)
Similarity:	82/201 - (40%)	Gaps:	22/201 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 ARGSRFTDADGN-GNGAGSQGGGVAARDR--SRERRNCRVYISNIPYDYRWQDLKDLFRRIVGSI 84
            |||.|   .||: |:|....|...:.||:  ...|...|:.:.|:.....||||||..|: .|.:
Human    70 ARGPR---RDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQ-AGEV 130

  Fly    85 EYVQLFFDESGKARGCGIVEFKDPENVQKALEKMNRYEVNGRELVVKEDH--GEQRDQYGRI--- 144
            .|.    |.....:..|::||....::::||||::..|||||::.:.||.  ..:|..|.|.
Human   131 TYA----DAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSH 191

  Fly   145 ------VRDGGGGGGGGGGVQGGNGGNNGGGGGGGRDHMDDRDRGFSRRDDDRLSGRNNFNMMSN 203
                  .|.........|..:..:..:......|.|.....|.|..||....:...|:.....|.
Human   192 SRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSR 256

  Fly   204 DYNNSS 209
            ..::|:
Human   257 SRSHSA 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rump	NP_649899.1	PABP-1234	48..435	CDD:130689	43/175 (25%)
		RRM1_hnRNPM_like	58..133	CDD:240831	24/74 (32%)
		RRM2_hnRNPM_like	234..307	CDD:240832
		RRM	<543..>631	CDD:223796
		RRM_SF	565..630	CDD:302621
SRSF4	NP_005617.2	RRM1_SRSF4_like	3..72	CDD:240783	1/1 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	72..95		8/25 (32%)
		RRM2_SRSF4_like	104..175	CDD:241044	24/75 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	169..494		16/94 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810