DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rump and Srsf4

DIOPT Version :9

Sequence 1:	NP_649899.1	Gene:	rump / 41138	FlyBaseID:	FBgn0267790	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_001356237.1	Gene:	Srsf4 / 57317	MGIID:	1890577	Length:	496	Species:	Mus musculus

Alignment Length:	196	Identity:	50/196 - (25%)
Similarity:	79/196 - (40%)	Gaps:	43/196 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 ARGSRFTDADGN-GNGAGSQGGGVAARDR--SRERRNCRVYISNIPYDYRWQDLKDLFRRIVGSI 84
            |||.|   .||: |:|....|...:.||:  ...|...|:.:.|:.....||||||..|: .|.:
Mouse    75 ARGPR---RDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQ-AGEV 135

  Fly    85 EYVQLFFDESGKARGCGIVEFKDPENVQKALEKMNRYEVNGRELVVKEDH--GEQRDQYGRIVRD 147
            .|.    |.....:..|::||....::::||||::..|||||::.:.||.  ..:|..|.|
Mouse   136 TYA----DAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSR---- 192

  Fly   148 GGGGGGGGGGVQGGNGGNNGGGGGGGRDHMDDRDRG-FSRRDDDRLSGRNNFNMMSNDYNNSSNY 211
                                     .|.|...|.|. .||:...|.....:.:..|...:.|.::
Mouse   193 -------------------------SRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSH 232

  Fly   212 N 212
            :
Mouse   233 S 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rump	NP_649899.1	PABP-1234	48..435	CDD:130689	41/170 (24%)
		RRM1_hnRNPM_like	58..133	CDD:240831	24/74 (32%)
		RRM2_hnRNPM_like	234..307	CDD:240832
		RRM	<543..>631	CDD:223796
		RRM_SF	565..630	CDD:302621
Srsf4	NP_001356237.1	RRM_SF	<42..77	CDD:388407	1/1 (100%)
		RRM2_SRSF4_like	109..180	CDD:241044	24/75 (32%)
		U2AF_lg	250..>361	CDD:273727
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900