Protein Alignment rump and hnrnpm

DIOPT Version :10

• Sequence 1: NP_649899.1
• Gene: rump / 41138
• FlyBaseID: FBgn0267790
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001243560.1
• Gene: hnrnpm / 555643
• ZFINID: ZDB-GENE-030131-6898
• Length: 686
• Species: Danio rerio
• Alignment Length: 750
• Identity: 231/750 - (30%)
• Similarity: 323/750 - (43%)
• Gaps: 191/750 - (25%)

  Fly     1 MSMDAS-------NSVESREKERDRRGRGARGSRFTDADGNGNGAGSQGGGVAARDRSRERRNCR 58
            ||.:||       |:|..:.....|:.|..:                :|||......|...:...
Zfish     1 MSTEASPEKTGQGNAVNGKSNHESRKERPPK----------------RGGGGRFEPYSNPNKRYS 49

  Fly    59 VYISNIPYDYRWQDLKDLFRRIVGSIEYVQLFFDESGKARGCGIVEFKDPENVQKALEKMNRYEV 123
            |::||||||.:||.||||.:..||.:.||:...|..||:|||.:|||:..|.::||:||:|::.:
Zfish    50 VFVSNIPYDVKWQTLKDLMKEKVGEVTYVEHLMDGEGKSRGCAVVEFRTEELMKKAVEKVNKHVM 114

  Fly   124 NGRELVVKEDHG---EQRDQYGRIVRDGGGGGGGGGGVQGGNGGNNGGGGGGGRDHMDDRDRGFS 185
            |||.|.||||..   .||:      .:.|.|||||||...|.||..|||.|||..       |..
Zfish   115 NGRPLKVKEDPDGVISQRE------ANRGHGGGGGGGGPPGMGGGMGGGMGGGMG-------GMG 166

  Fly   186 RRDDDRLSGRNNF--NMMSNDYNNSSNYNLYGLSASFLESLGISGPLHNKVFVANLDYKVDNKKL 248
            .......|...|.  ::|:|.  |..|..::||.|         |.:.:.:|||||||||..|||
Zfish   167 MGPGPGSSSMVNIPPSLMNNP--NIPNEVIHGLQA---------GKIGSTIFVANLDYKVGWKKL 220

  Fly   249 KQVFKLAGKVQSVDLSLDKEGNSRGFAVIEYDHPVEAVQAISMLDRQMLFDRRMTVRLD------ 307
            |:||.:||.|...|:..||:|.|||...:.:|.|:|||||:||.:.|:||:|.|.|:||
Zfish   221 KEVFGMAGMVVRADILEDKDGKSRGMGTVTFDMPIEAVQAVSMFNGQLLFNRVMHVKLDEKSLPK 285

  Fly   308 -------RIPDKNEGIKLPEGLGGVGIGLGPNGEPL------RDVAHNLPNGGQ------SQGQL 353
                   |.|      .||.||.|||:||||.|:|:      |....|:..||.      ..|::
Zfish   286 GDFAPPERAP------ALPRGLSGVGLGLGPGGQPIDATQLNRGGMGNMGPGGMDGMGYGGMGRM 344

  Fly   354 LGNAQQGSQLGSVGSQPNSSAVSNATTNLLNNLTGVMFG---------NHAAVQPSPVAPVQKPS 409
            .|....|...|..|...|......:....:|::...|.|         |...:..|.........
Zfish   345 GGMDNFGGGGGGGGGMNNMDRFGPSGMGRMNDMDRGMGGGFDRDFSGRNDMGMSRSNFGDSFDRG 409

  Fly   410 LGNNTG-----------SGGLN------------------------------------------L 421
            :||:.|           |||::                                          |
Zfish   410 MGNSMGMDRMNSGMDRLSGGIDRMGGGGGGGGMDRMGGGGGGGGMDRMSDLDRMGSSFDRMGSGL 474

  Fly   422 NNLNPSI---------LAAVVGNLGNQG----GNLSNPLLSSSL---SNLGLNLGNSGNDDNLPP 470
            :.|.||:         ::..|..:|..|    |:.|...:|..:   |.:|::..|:|.|
Zfish   475 DRLGPSMDRMGSGLDRMSTSVDRMGPGGFDRLGSSSMDRMSGGMDFASPMGMDRMNTGLD----- 534

  Fly   471 SNVGLSNNYSSGGTGGGNSYSSGNNYSGGGGSSNLGYNAYSSSGGMG-GGNGGVGVDGNDYNTGN 534
               .:.:|:...|:||.:.:|||.:..|            ||...|| ||.||......|.:.||
Zfish   535 ---RMGSNFDRMGSGGMDRFSSGLDRMG------------SSMDRMGSGGIGGQFDRPGDMDRGN 584

  Fly   535 PLDVYGGGSNVGNSNVGSANAVGASRKSDTIIIKNVPITCTWQTLRDKFREIGDVKFAEI----- 594
            ....:||....|....|.|||    ||...|.::|:|...||:.|:|.|...|.|::|:|
Zfish   585 FGSPFGGSGQGGGPGSGGANA----RKGCQIFVRNLPFDFTWKMLKDTFNSCGMVQYADIKMENG 645

  Fly   595 RGNDVGVVRFFKERDAELAIALMDGSRLDGRNIKV 629
            :....|||||.....||.|...|:|.||:||.|.|
Zfish   646 KSKGCGVVRFDNPETAERACRTMNGYRLNGREIDV 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rump	NP_649899.1	PABP-1234	48..435	CDD:130689	154/487 (32%)
		RRM1_hnRNPM_like	58..133	CDD:409819	38/74 (51%)
		RRM2_hnRNPM_like	234..307	CDD:409820	40/72 (56%)
		RRM_SF	565..629	CDD:473069	27/68 (40%)
hnrnpm	NP_001243560.1	RRM1_hnRNPM	49..124	CDD:410058	38/74 (51%)
		RRM2_hnRNPM	204..279	CDD:410060	40/74 (54%)
		RRM3_hnRNPM	610..686	CDD:410062	27/70 (39%)