DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rump and Srsf6

DIOPT Version :9

Sequence 1:	NP_649899.1	Gene:	rump / 41138	FlyBaseID:	FBgn0267790	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_001014207.2	Gene:	Srsf6 / 362264	RGDID:	1359241	Length:	339	Species:	Rattus norvegicus

Alignment Length:	244	Identity:	62/244 - (25%)
Similarity:	99/244 - (40%)	Gaps:	40/244 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SMDASNSV---ESREKERDR----RGRGARGSRFTDADGNGNGAGSQGGGVAARDRSRE------ 53
            |.||.::|   .|:|...:|    ..||.|    .|.||...|:.|.|||.::|..|..
  Rat    45 SRDADDAVYELNSKELCGERVIVEHARGPR----RDRDGYSYGSRSGGGGYSSRRTSGRDKYGPP 105

  Fly    54 -RRNCRVYISNIPYDYRWQDLKDLFRRIVGSIEYVQLFFDESGKARGCGIVEFKDPENVQKALEK 117
             |...|:.:.|:.....|||||| |.|..|.:.|.....:.:.:    |::||:...::::||:|
  Rat   106 VRTEYRLIVENLSSRCSWQDLKD-FMRQAGEVTYADAHKERTNE----GVIEFRSYSDMKRALDK 165

  Fly   118 MNRYEVNGRELVVKEDHGEQRDQYGRIVRDGGGGGGGGGGVQGGNGGNNGGGGGGGRDHMDDRDR 182
            ::..|:|||.:.:.||......:     |...|........:.....:........|.....|.|
  Rat   166 LDGTEINGRNIRLIEDKPRTSHR-----RSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSR 225

  Fly   183 GFSR---RDDDRLSGRNNFNMM---------SNDYNNSSNYNLYGLSAS 219
            ..||   |...|..||.:.:..         |:.::.|.:.:.||.|.|
  Rat   226 SRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDKYGKSRS 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rump	NP_649899.1	PABP-1234	48..435	CDD:130689	44/191 (23%)
		RRM1_hnRNPM_like	58..133	CDD:240831	22/74 (30%)
		RRM2_hnRNPM_like	234..307	CDD:240832
		RRM	<543..>631	CDD:223796
		RRM_SF	565..630	CDD:302621
Srsf6	NP_001014207.2	RRM_SF	1..72	CDD:418427	7/26 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	75..103		10/27 (37%)
		RRM2_SRSF6	110..182	CDD:410159	23/76 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	176..339		19/104 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900