DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rump and srsf5a

DIOPT Version :9

Sequence 1:	NP_649899.1	Gene:	rump / 41138	FlyBaseID:	FBgn0267790	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_957161.1	Gene:	srsf5a / 335396	ZFINID:	ZDB-GENE-030131-7336	Length:	259	Species:	Danio rerio

Alignment Length:	204	Identity:	56/204 - (27%)
Similarity:	81/204 - (39%)	Gaps:	43/204 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 EKERDRRGRG---ARGSRFTDADGNGNGAGSQGGGVAARDRSRERRNCRVYISNIPYDYRWQDLK 74
            |..|.|||||   ..|.||:...|...  .|:.||  :|.....|...|:.:.|:.....|||||
Zfish    70 EHARSRRGRGGGPGMGGRFSPRFGGYR--QSRSGG--SRYGPPVRTEHRIIVENLSSRISWQDLK 130

  Fly    75 DLFRRIVGSIEYVQLFFDESGKARGCGIVEFKDPENVQKALEKMNRYEVNGRELVVKEDHGEQRD 139
            ||.|: ||.:.:|    |.....:..|:|||....:::.|:||::..::|||:|.:.||....|.
Zfish   131 DLMRK-VGEVTFV----DAHRTKKNEGVVEFASHSDMKNAIEKLDGTDLNGRKLKLYEDRKRNRS 190

  Fly   140 QYGRIVRDGGGGGGGGGGVQGGNGGNNGGGGGGGRDHMDDRDRGFSR-RDDDRLSGRNNFNMMSN 203
            :                              ...|.....|.|..|| |..:|.|.|:....:|.
Zfish   191 R------------------------------SRSRSRSSSRSRSPSRSRSPERGSKRSRSRSLSR 225

  Fly   204 DYNNSSNYN 212
            .....|..|
Zfish   226 TPEKKSTSN 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rump	NP_649899.1	PABP-1234	48..435	CDD:130689	42/166 (25%)
		RRM1_hnRNPM_like	58..133	CDD:240831	25/74 (34%)
		RRM2_hnRNPM_like	234..307	CDD:240832
		RRM	<543..>631	CDD:223796
		RRM_SF	565..630	CDD:302621
srsf5a	NP_957161.1	RRM1_SRSF4_like	5..72	CDD:240783	1/1 (100%)
srsf5a	NP_957161.1	RRM2_SRSF4_like	113..184	CDD:241044	25/75 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900