DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rump and Tia1

DIOPT Version :9

Sequence 1:	NP_649899.1	Gene:	rump / 41138	FlyBaseID:	FBgn0267790	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	XP_006236890.1	Gene:	Tia1 / 312510	RGDID:	1305742	Length:	387	Species:	Rattus norvegicus

Alignment Length:	398	Identity:	77/398 - (19%)
Similarity:	130/398 - (32%)	Gaps:	135/398 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 VYISNIPYDYRWQDLKDLFRRIVGSIEYVQLFFDE-SGKARGCGIVEFKDPENVQKALEKMNRYE 122
            :|:.|:..|.....:..||.:| |..:..::..|: :|....| .|||.:..:...||..||..:
  Rat     9 LYVGNLSRDVTEALILQLFSQI-GPCKNCKMIMDQTAGNDPYC-FVEFHEHRHAAAALAAMNGRK 71

  Fly   123 VNGRELVV---------KEDHGE------QRDQ-------------------------YGRI--- 144
            :.|:|:.|         |:|...      ||.|                         :|||
  Rat    72 IMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 136

  Fly   145 --VRDGGGGGGGGGG-------------VQGGNGGNNGGGGGGGRDHMDDRDRGFSRRDD-DRLS 193
              |:|...|...|.|             :|     ..||...|||   ..|....:|:.. .:.:
  Rat   137 RVVKDMATGKSKGYGFVSFFNKWDAENAIQ-----QMGGQWLGGR---QIRTNWATRKPPAPKST 193

  Fly   194 GRNNFNMMSNDYNNSSNYNLYGLSASFLESLGISGPLHNKVFVANLDYKVDNKKLKQVFKLAGKV 258
            ..:|...:|.|                 |.:..|.|.:..|:...:...:..:.::|.|...|::
  Rat   194 YESNTKQLSYD-----------------EVVSQSSPGNCTVYCGGVTSGLTEQLMRQTFSPFGQI 241

  Fly   259 QSVDLSLDKEGNSRGFAVIEYDHPVEAVQAISMLDRQML--------FDRRMTVRLDRIPDKNEG 315
            ..:.:..||     |::.|.:.....|..||..::...:        :.:.....::.:..:|:
  Rat   242 MEIRVFPDK-----GYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQ- 300

  Fly   316 IKLPEGLGGVGIGLGPNGEPLRDVAHNLPNGGQSQGQLLGNAQQ-------GSQLGSVG--SQPN 371
            |..|...|                         ..||..|||||       |.|:.:.|  .||.
  Rat   301 IGYPPAYG-------------------------QWGQWYGNAQQIGQYVPNGWQVPAYGMYGQPW 340

  Fly   372 SSAVSNAT 379
            |....|.|
  Rat   341 SQQGFNQT 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rump	NP_649899.1	PABP-1234	48..435	CDD:130689	77/398 (19%)
		RRM1_hnRNPM_like	58..133	CDD:240831	21/83 (25%)
		RRM2_hnRNPM_like	234..307	CDD:240832	11/80 (14%)
		RRM	<543..>631	CDD:223796
		RRM_SF	565..630	CDD:302621
Tia1	XP_006236890.1	ELAV_HUD_SF	6..281	CDD:273741	58/303 (19%)
		RRM_SF	8..82	CDD:302621	20/74 (27%)
		RRM2_TIA1	106..185	CDD:241062	15/86 (17%)
		RRM3_TIAR	215..287	CDD:241064	11/76 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900