Protein Alignment rump and Myef2

DIOPT Version :10

• Sequence 1: NP_649899.1
• Gene: rump / 41138
• FlyBaseID: FBgn0267790
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001155889.1
• Gene: Myef2 / 17876
• MGIID: 104592
• Length: 591
• Species: Mus musculus
• Alignment Length: 677
• Identity: 211/677 - (31%)
• Similarity: 302/677 - (44%)
• Gaps: 182/677 - (26%)

  Fly     1 MSMDASNSVESREKERDRRGRG-ARGSRFTDADGNGN-GAGSQGGGVAARDRSRERRNCRVYISN 63
            :.|:...||:..:.:...:..| .:.:||.....:.| |.|.:.|         ..|| ||:|||
Mouse    43 VKMENDESVKEEKSDLKEKSTGNKKANRFHPYSKDKNSGTGEKKG---------PNRN-RVFISN 97

  Fly    64 IPYDYRWQDLKDLFRRIVGSIEYVQLFFDESGKARGCGIVEFKDPENVQKALEKMNRYEVNGREL 128
            ||||.:||.:|||.|..||.:.||:||.|..||:||||:|||||.|.|:||||.||:|:::||.|
Mouse    98 IPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPL 162

  Fly   129 VVKED-HGE------QRDQYGRIVRDGGGGGGGGGGVQGGNGGNNGGGGGGGRDHMDDRDRGFSR 186
            .:||| .||      ||.               |...||.:..:.|.|
Mouse   163 NIKEDPDGENARRALQRT---------------GTSFQGSHASDVGSG----------------- 195

  Fly   187 RDDDRLSGRNNFNMMSNDYNNSSNYNLYGLSASFLESLGI---------SGPLHNKVFVANLDYK 242
                                      |..|..|.|.:..|         :|.|.:.:||||||:|
Mouse   196 --------------------------LVNLPPSILNNPNIPPEVISNLQAGRLGSTIFVANLDFK 234

  Fly   243 VDNKKLKQVFKLAGKVQSVDLSLDKEGNSRGFAVIEYDHPVEAVQAISMLDRQMLFDRRMTVRLD 307
            |..||||:||.:||.|:..|:..||:|.|||...:.::..:||||||||.:.|.||||.|.|::|
Mouse   235 VGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKMD 299

  Fly   308 --RIPDK------NEGIKLPEGLGGVGIGLGPNGEPLRDVAHNLPNGGQSQGQLLGNAQQGSQLG 364
              .:|.:      ::..:||.||||:|:||||.|:|:                      ..|||
Mouse   300 DKSVPHEDYRSHDSKTSQLPRGLGGIGMGLGPGGQPI----------------------SASQL- 341

  Fly   365 SVGSQPNSSAVSNATTNLLNNLTGVMFGNHAAVQPSPVAPVQKPSLGN-NTGSGGLNLNNLNPSI 428
                                |:|||| ||   :.||.:. :..|..|. |...||:....|....
Mouse   342 --------------------NITGVM-GN---LGPSGMG-MDGPGFGGVNRIGGGVGFGGLEAMN 381

  Fly   429 LAAVVGNLGNQGGNLSNPLLSSSLSNLGLNLGNSGNDDNLPPSNVGLSNNYSSGGTGGGNSYSSG 493
            ..|..|.:|.. |.|....::||:..      :.|..|      :|||..:.......|::...|
Mouse   382 SMAGFGGVGRM-GELYRGAMTSSMER------DFGRGD------IGLSRGFGDSFGRLGSAMIGG 433

  Fly   494 NNYSGGGGSSNLGYNAYSSSGGMGG-----GNGGVGVD--GNDYNTGNP---------LDVYGGG 542
              ::|..|:||:|......||.|.|     |..|:|:|  .:.::...|         :||..|.
Mouse   434 --FAGRIGASNMGPVGTGISGSMSGMSTVTGGMGMGLDRMSSSFDRMGPGIGAILERSIDVDRGF 496

  Fly   543 SNVGNSNVGSANAVGASRKSDTIIIKNVPITCTWQTLRDKFREIGDVKFAEI-----RGNDVGVV 602
            .: |....|..:.:|:  |.:.|.::|:|...|||.|::||.:.|.|.||||     :....|.|
Mouse   497 LS-GPMGSGMRDRLGS--KGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTV 558

  Fly   603 RFFKERDAELAIALMDGSRLDGRNIKV 629
            ||.....||.|..:|:|.::.||.|.|
Mouse   559 RFESAESAEKACRIMNGIKISGREIDV 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rump	NP_649899.1	PABP-1234	48..435	CDD:130689	139/411 (34%)
		RRM1_hnRNPM_like	58..133	CDD:409819	46/74 (62%)
		RRM2_hnRNPM_like	234..307	CDD:409820	39/72 (54%)
		RRM_SF	565..629	CDD:473069	27/68 (40%)
Myef2	NP_001155889.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..92		12/58 (21%)
		RRM1_MYEF2	92..167	CDD:410059	46/74 (62%)
		PABP-1234	115..>587	CDD:130689	184/595 (31%)
		RRM2_MYEF2	224..299	CDD:410061	39/74 (53%)
		RRM3_MYEF2	515..591	CDD:410063	28/71 (39%)