DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rump and SNRNP35

DIOPT Version :9

Sequence 1:	NP_649899.1	Gene:	rump / 41138	FlyBaseID:	FBgn0267790	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_851030.1	Gene:	SNRNP35 / 11066	HGNCID:	30852	Length:	251	Species:	Homo sapiens

Alignment Length:	144	Identity:	40/144 - (27%)
Similarity:	64/144 - (44%)	Gaps:	28/144 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   218 ASFLESLGISGPLHNKVFVANLDYKVDNKKLKQVFKLAGKVQSVDLSLD-KEGNSRGFAVIEYDH 281
            |.::.:.|:.|.....:|||.|:.:....|||:||...|.::.:.|..| ..|.|:|:|.|||..
Human    42 ARYVPNKGVIGDPLLTLFVARLNLQTKEDKLKEVFSRYGDIRRLRLVRDLVTGFSKGYAFIEYKE 106

  Fly   282 PVEAVQAIS-----MLDRQMLFDRRMTVRLDRIPDKNEGIK--LPEGLGGVGIG---------LG 330
            ....::|..     ::|:..:|   :...|:|.      :|  :|..||| |:|         .|
Human   107 ERAVIKAYRDADGLVIDQHEIF---VDYELERT------LKGWIPRRLGG-GLGGKKESGQLRFG 161

  Fly   331 PNGEPLRDVAHNLP 344
            ....|.|... |||
Human   162 GRDRPFRKPI-NLP 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rump	NP_649899.1	PABP-1234	48..435	CDD:130689	40/144 (28%)
		RRM1_hnRNPM_like	58..133	CDD:240831
		RRM2_hnRNPM_like	234..307	CDD:240832	22/78 (28%)
		RRM	<543..>631	CDD:223796
		RRM_SF	565..630	CDD:302621
SNRNP35	NP_851030.1	RRM_snRNP35	53..142	CDD:240683	25/97 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900