DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8149 and THO1

DIOPT Version :9

Sequence 1:	NP_649898.1	Gene:	CG8149 / 41137	FlyBaseID:	FBgn0037700	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_010985.1	Gene:	THO1 / 856792	SGDID:	S000000865	Length:	218	Species:	Saccharomyces cerevisiae

Alignment Length:	253	Identity:	55/253 - (21%)
Similarity:	95/253 - (37%)	Gaps:	47/253 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SDVTKMKVADLKRELKLRGLAVNGNKTELQDRLQTALLEGDLSLEDSAIADAIDDDDVSFTDEDE 68
            :|.:.:.|..||..|..|.|:|.|.|.||..||                   |.||:.|   :.|
Yeast     2 ADYSSLTVVQLKDLLTKRNLSVGGLKNELVQRL-------------------IKDDEES---KGE 44

  Fly    69 HKLLGDENDDELLKSP--VSTPTTVAIPDLLAEEKTSSAPDAAAPTKKIVLKRNNSQQ--STGTV 129
            .::...|.:.|....|  :..|   |..::..:::.||.|......|    :.|...|  |.|..
Yeast    45 SEVSPQEQNQEQGSEPAAIEEP---ASQNITEKKEVSSEPKETNEPK----EENKDVQKPSDGPS 102

  Fly   130 ASTGTTPSKENEAPAAAASDSTGETPTKKHKPIVVGPKTEGEKPSGDKKLNQLTAQERLELRAKK 194
            |    |.|:..:|.|:.|:.:......|.....::..|.......|..:.:..:.|.::. |.:|
Yeast   103 A----TASENEQAAASTAAPALSPEEIKAKALDLLNKKLHRANKFGQDQADIDSLQRQIN-RVEK 162

  Fly   195 FGITPPAVANTATAVAVAINKSSSASITANKG-----NKETEEQQKEALKKRAERFGF 247
            ||:.    .|:..|..:.:....:...:.|.|     ||....:.:.:..:|..|.|:
Yeast   163 FGVD----LNSKLAEELGLVSRKNEPESGNNGKFKNRNKNANNRSRVSKNRRGNRSGY 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8149	NP_649898.1	SAP	6..40	CDD:280251	13/33 (39%)
THO1	NP_010985.1	SAP	4..38	CDD:396567	14/52 (27%)
		PRK13108	<39..109	CDD:237284	18/83 (22%)
		Tho1_MOS11_C	127..164	CDD:408375	5/37 (14%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103733
Panther	1	1.100	-	-	LDO	PTHR46551
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.000