DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RhoL and RHO3

DIOPT Version :9

Sequence 1:	NP_001247003.1	Gene:	RhoL / 41136	FlyBaseID:	FBgn0014380	Length:	214	Species:	Drosophila melanogaster
Sequence 2:	NP_012148.1	Gene:	RHO3 / 854688	SGDID:	S000001380	Length:	231	Species:	Saccharomyces cerevisiae

Alignment Length:	225	Identity:	87/225 - (38%)
Similarity:	118/225 - (52%)	Gaps:	36/225 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 TANITKSPRPLKITIVGDGMVGKTCMLITYTRNEFPEEYIPTVFDNHACNIAVDDRDYNLTLWDT 90
            :|:.:..|...||.|:|||..|||.:|..:||..|||.|.||||:|:..:|.||.:...|:||||
Yeast     7 SASTSNKPIERKIVILGDGACGKTSLLNVFTRGYFPEVYEPTVFENYIHDIFVDSKHITLSLWDT 71

  Fly    91 AGQEDYERLRPLSYPSTNCFLLCYSISSRTSFENVKSKWWPEIRHFSAHVPVVLVGTKLDLR--- 152
            ||||:::|||.|||..|.|.:||:||.||.|.|||::||..||......|.:|||..|.|||
Yeast    72 AGQEEFDRLRSLSYSDTQCIMLCFSIDSRDSLENVQNKWVGEITDHCEGVKLVLVALKCDLRNNE 136

  Fly   153 ---------------------------IPNSEKFVTTQEGKKMRKEIHAFNLVECSAKKKQNLQQ 190
                                       ..|.:..::.:||..|.|:|.|...:|||||..:.:.:
Yeast   137 NESNAITPNNIQQDNSVSNDNGNNINSTSNGKNLISYEEGLAMAKKIGALRYLECSAKLNKGVNE 201

  Fly   191 VFEEAVRA------VERKPKTTSKQSCKIL 214
            .|.||.|.      |..:.|:.|..||.|:
Yeast   202 AFTEAARVALTAGPVATEVKSDSGSSCTIM 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoL	NP_001247003.1	Rho	36..198	CDD:206641	78/191 (41%)
RhoL	NP_001247003.1	RHO	38..202	CDD:197554	79/199 (40%)
RHO3	NP_012148.1	Rho3	17..231	CDD:206706	84/213 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770