Protein Alignment RhoL and Rhoh

DIOPT Version :10

• Sequence 1: NP_001247003.1
• Gene: RhoL / 41136
• FlyBaseID: FBgn0014380
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_001074574.1
• Gene: Rhoh / 74734
• MGIID: 1921984
• Length: 191
• Species: Mus musculus
• Alignment Length: 186
• Identity: 72/186 - (38%)
• Similarity: 107/186 - (57%)
• Gaps: 8/186 - (4%)

  Fly    36 LKITIVGDGMVGKTCMLITYTRNEFPEEYIPTVFDNHACNIAVDDRDYNLTLWDTAGQEDYERLR 100
            :|..:|||..||||.:|:.:|...|||.|.|||::|...::.:|....:|.||||||.:.:..:|
Mouse     5 IKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTAGNDAFRSIR 69

  Fly   101 PLSYPSTNCFLLCYSISSRTSFENVKSKWWPEIRHFSAHVPVVLVGTKLDLRI--PNSEKFVTTQ 163
            ||||...:..|:|||:::..||.|:|:||..|||......||::|.|:.|.|.  |:....:...
Mouse    70 PLSYQQADVVLMCYSVANHNSFLNLKNKWISEIRSNLPCTPVLVVATQTDQREVGPHRASCINAI 134

  Fly   164 EGKKMRKEIHAFNLVECSAKKKQNLQQVFEEAVRAV------ERKPKTTSKQSCKI 213
            |||::.:::.|...:||||...:.:|||||.|||..      ..:.|..|...|||
Mouse   135 EGKRLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRRKLFSINECKI 190

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoL	NP_001247003.1	Rho	36..198	CDD:206641	66/163 (40%)
Rhoh	NP_001074574.1	Rho	5..169	CDD:206641	66/163 (40%)
		Effector region. /evidence=ECO:0000250	33..41		4/7 (57%)
		Interaction with ZAP70. /evidence=ECO:0000269|PubMed:17028588	73..86		5/12 (42%)