DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoL and Rhot1

DIOPT Version :9

Sequence 1:	NP_001247003.1	Gene:	RhoL / 41136	FlyBaseID:	FBgn0014380	Length:	214	Species:	Drosophila melanogaster
Sequence 2:	XP_006533949.1	Gene:	Rhot1 / 59040	MGIID:	1926078	Length:	752	Species:	Mus musculus

Alignment Length:	170	Identity:	45/170 - (26%)
Similarity:	87/170 - (51%)	Gaps:	10/170 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 RPLKITIVGDGMVGKTCMLITYTRNEFPEEYIPTVFD-NHACNIAVDDRDYNLTLWDTAGQEDYE 97
            :.::|.:||:..||||.::::....|||||..|...: ....::..:....::..:..|.|.|.:
Mouse    16 KDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQ 80

  Fly    98 RLRPLSYPSTNCFLLCYSISSRTSFENVKSKWWPEIRHFS---AHVPVVLVGTKLDLRIPNSEKF 159
            ..:.:|..:..|  :.|:::::.|.:.|.|:|.|.|...:   :.:|::|||.|.||...:|.:.
Mouse    81 LHQEISQANVIC--IVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMET 143

  Fly   160 VTTQEGKKMRKEIHAFNLVECSAKKKQNLQQVFEEAVRAV 199
            :.    ..|.:.......||||||..:|:.::|..|.:||
Mouse   144 IL----PIMNQYTEIETCVECSAKNLKNISELFYYAQKAV 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoL	NP_001247003.1	Rho	36..198	CDD:206641	43/165 (26%)
RhoL	NP_001247003.1	RHO	38..202	CDD:197554	45/166 (27%)
Rhot1	XP_006533949.1	Miro1	16..182	CDD:206680	45/170 (26%)
		EF_assoc_2	232..316	CDD:369829
		EF_assoc_1	354..423	CDD:369828
		Miro2	428..593	CDD:206679
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1464
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950