DRSC/TRiP Functional Genomics Resources

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Protein Alignment RhoL and RHOU

DIOPT Version :9

Sequence 1:NP_001247003.1 Gene:RhoL / 41136 FlyBaseID:FBgn0014380 Length:214 Species:Drosophila melanogaster
Sequence 2:NP_067028.1 Gene:RHOU / 58480 HGNCID:17794 Length:258 Species:Homo sapiens


Alignment Length:207 Identity:84/207 - (40%)
Similarity:125/207 - (60%) Gaps:21/207 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 RGKKPGMTANITKSPRPLKITIVGDGMVGKTCMLITYTRNEFPEEYIPTVFDNHACNIAVDDRDY 83
            ||:..|...      |.:|..:||||.||||.::::||.|.:|.|||||.|||.:..::||.|..
Human    39 RGRAGGAEG------RGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPV 97

  Fly    84 NLTLWDTAGQEDYERLRPLSYPSTNCFLLCYSISSRTSFENVKSKWWPEIRHFSAHVPVVLVGTK 148
            .|.|.|||||:::::||||.|.:|:.||||:|:.|.:||:||..||.||||......|::||||:
Human    98 RLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQ 162

  Fly   149 LDLR---------IPNSEKFVTTQEGKKMRKEIHAFNLVECSAKKKQNLQQVFEEAVRA------ 198
            .|||         ....||.|..:..|...:||.|.:.:||||..::||::||:.|:.|      
Human   163 SDLREDVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQYSD 227

  Fly   199 VERKPKTTSKQS 210
            .:::||.:..::
Human   228 TQQQPKKSKSRT 239

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RhoLNP_001247003.1 Rho 36..198 CDD:206641 77/170 (45%)
RHO 38..202 CDD:197554 77/178 (43%)
RHOUNP_067028.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..45 2/5 (40%)
Wrch_1 50..222 CDD:133330 77/171 (45%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0393
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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