Protein Alignment RhoL and RND3

DIOPT Version :10

• Sequence 1: NP_001247003.1
• Gene: RhoL / 41136
• FlyBaseID: FBgn0014380
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_005159.1
• Gene: RND3 / 390
• HGNCID: 671
• Length: 244
• Species: Homo sapiens
• Alignment Length: 184
• Identity: 66/184 - (35%)
• Similarity: 104/184 - (56%)
• Gaps: 10/184 - (5%)

  Fly    37 KITIVGDGMVGKTCMLITYTRNEFPEEYIPTVFDNHACNIAVDDRDYNLTLWDTAGQEDYERLRP 101
            ||.:|||...|||.:|..:.::.|||.|:||||:|:..:..:|.:...|:||||:|...|:.:||
Human    25 KIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGSPYYDNVRP 89

  Fly   102 LSYPSTNCFLLCYSISSRTSFENVKSKWWPEIRHFSAHVPVVLVGTKLDLRIPNS---------E 157
            ||||.::..|:|:.||...:.::|..||..||:.|..:..::|||.|.|||...|         :
Human    90 LSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQ 154

  Fly   158 KFVTTQEGKKMRKEIHAFNLVECSAKKKQN-LQQVFEEAVRAVERKPKTTSKQS 210
            ..|:..:|..|.|:|.|...:||||.:.:| ::.:|..|..|...|.....|::
Human   155 TPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVNKTNKNVKRN 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoL	NP_001247003.1	Rho	36..198	CDD:206641	63/170 (37%)
RND3	NP_005159.1	Rnd3_RhoE_Rho8	19..200	CDD:206735	64/174 (37%)
		Effector region. /evidence=ECO:0000255	52..60		5/7 (71%)