Protein Alignment RhoL and Rac1

DIOPT Version :10

• Sequence 1: NP_001247003.1
• Gene: RhoL / 41136
• FlyBaseID: FBgn0014380
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_599193.1
• Gene: Rac1 / 363875
• RGDID: 619755
• Length: 192
• Species: Rattus norvegicus
• Alignment Length: 189
• Identity: 101/189 - (53%)
• Similarity: 131/189 - (69%)
• Gaps: 10/189 - (5%)

  Fly    36 LKITIVGDGMVGKTCMLITYTRNEFPEEYIPTVFDNHACNIAVDDRDYNLTLWDTAGQEDYERLR 100
            :|..:||||.|||||:||:||.|.||.|||||||||::.|:.||.:..||.||||||||||:|||
  Rat     4 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLR 68

  Fly   101 PLSYPSTNCFLLCYSISSRTSFENVKSKWWPEIRHFSAHVPVVLVGTKLDLRIPNS--EKF---- 159
            |||||.|:.||:|:|:.|..|||||::||:||:||...:.|::|||||||||....  ||.
  Rat    69 PLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKK 133

  Fly   160 ---VTTQEGKKMRKEIHAFNLVECSAKKKQNLQQVFEEAVRAVERKPKTTS-KQSCKIL 214
               :|..:|..|.|||.|...:||||..::.|:.||:||:|||...|.... |:.|.:|
  Rat   134 LTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoL	NP_001247003.1	Rho	36..198	CDD:206641	94/170 (55%)
Rac1	NP_599193.1	Rac1_like	3..176	CDD:206663	95/171 (56%)
		Effector region. /evidence=ECO:0000255	32..40		7/7 (100%)
		Polybasic region, required for nuclear import. /evidence=ECO:0000250|UniProtKB:P63000	179..188		2/8 (25%)