DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoL and miro-1

DIOPT Version :9

Sequence 1:	NP_001247003.1	Gene:	RhoL / 41136	FlyBaseID:	FBgn0014380	Length:	214	Species:	Drosophila melanogaster
Sequence 2:	NP_500620.1	Gene:	miro-1 / 177238	WormBaseID:	WBGene00019544	Length:	625	Species:	Caenorhabditis elegans

Alignment Length:	167	Identity:	43/167 - (25%)
Similarity:	82/167 - (49%)	Gaps:	9/167 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LKITIVGDGMVGKTCMLITYTRNEFPEEYIPTVFDNHACNIAVDDRDYNLTLWDTAGQEDYERLR 100
            ::|.::||...|||.::::...:|:.:. :|...|.......|...:...::.|.:.:|:.|...
Worm    10 VRIVLIGDEGCGKTSLVMSLLEDEWVDA-VPRRLDRVLIPADVTPENVTTSIVDLSIKEEDENWI 73

  Fly   101 PLSYPSTNCFLLCYSISSRTSFENVKSKWWPEIRH-FSAH--VPVVLVGTKLDLRIPNSEKFVTT 162
            .......|...:.||::..::.:.:::||.|.||. |..:  .||:|||.|.|....|::|.:..
Worm    74 VSEIRQANVICVVYSVTDESTVDGIQTKWLPLIRQSFGEYHETPVILVGNKSDGTANNTDKILPI 138

  Fly   163 QEGKKMRKEIHAFNLVECSAKKKQNLQQVFEEAVRAV 199
            .|.   ..|:.  ..|||||:..:|:.::|..|.:||
Worm   139 MEA---NTEVE--TCVECSARTMKNVSEIFYYAQKAV 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoL	NP_001247003.1	Rho	36..198	CDD:206641	41/164 (25%)
RhoL	NP_001247003.1	RHO	38..202	CDD:197554	43/165 (26%)
miro-1	NP_500620.1	Miro1	9..173	CDD:206680	43/167 (26%)
		Ras	11..171	CDD:278499	43/166 (26%)
		EF_assoc_2	225..306	CDD:285547
		EF_assoc_1	352..417	CDD:285546
		Miro2	423..592	CDD:206679
		Gem1	425..608	CDD:224025
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1464
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950