Protein Alignment phu and alpi.1

DIOPT Version :9

• Sequence 1: NP_649897.4
• Gene: phu / 41135
• FlyBaseID: FBgn0043791
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_001014375.1
• Gene: alpi.1 / 541539
• ZFINID: ZDB-GENE-050327-78
• Length: 532
• Species: Danio rerio
• Alignment Length: 495
• Identity: 212/495 - (42%)
• Similarity: 293/495 - (59%)
• Gaps: 35/495 - (7%)

  Fly    57 DAVRSEERYAEYWQGLAAQTLDQQLESKLRLNTQLARNVMLFIGDGMSIPTITAGRVYLG----- 116
            |:....|:...||...|.:||...|...||:|.  |:|::||:||||.:.|::|.|:..|
Zfish    28 DSAAEWEKDPAYWNDQARRTLQTALTLPLRVNR--AKNIILFVGDGMGVSTVSAARILRGQMEGQ 90

  Fly   117 -GEEKQFAFEQFPYVGLSKTYCANMQVADSACTATAYLGGVKANYGTIGVSAAVQFKDCQAQAQA 180
             |||...|.:.|||:.||||||.:.||||||.|||||..|||||..|:|:||.....:|  ....
Zfish    91 SGEETILAMDTFPYLALSKTYCVDKQVADSASTATAYHCGVKANAKTVGLSAKAVAYEC--NTTF 153

  Fly   181 AHHVSSIAAWAQKQGMATGLVTTTSVTHASPAGVYAHLANRNWENDAEVVGD---NGDPDLCPDA 242
            .:.|.|:...|:.||.:.|:||||.|.|||||..|||..:|.|.:||:|..:   .|    |.|.
Zfish   154 GNEVFSVLHRAKAQGKSVGIVTTTRVQHASPAAAYAHSVSRKWYSDADVPSEARRQG----CKDI 214

  Fly   243 AAQLINSPVGQKLNVIMGGGRENFLPKGVTD----SSGAPGRRLDGRNLIDEWKN-QHTNSAQYV 302
            |.||:.:   ..::||:||||....|||..|    ||...|.|.|.:|||:.|.| :...:||||
Zfish   215 ATQLVTN---TDIDVILGGGRMYMTPKGTPDPEYSSSSHKGDRKDKKNLINVWLNARKGRNAQYV 276

  Fly   303 ENRRELLNLS-NHTSRVLGLFAPYHMAYHLDASPAEQPTLEEMVQSAMEILERQSAGRGYFLFVE 366
            .|:.:...:. ..|..::|||.|..|.:.:..:....|::.:|.:.|::||.:..  :|:|||||
Zfish   277 WNKEQFNAVDVKTTDCLMGLFEPKDMRFEVFRNRTRDPSIVDMTEKAIQILSKNP--KGFFLFVE 339

  Fly   367 GGRIDHGHHDTLALRAIDETAEFDKAVRFARSHTSTDDTLIVVSSDHSHTMSLAGYSSRKNDIFG 431
            ||||||||||.:|..|:.||..||:|::.|...||..|||.||::||||..:..|.:.|.|.|||
Zfish   340 GGRIDHGHHDGVAKLALTETIMFDRAIQRASELTSESDTLTVVTADHSHVFTFGGKTPRGNPIFG 404

  Fly   432 INDGQLAADDLPYATLSYANGPGYDSNYLREGGAVRRKNLRAINMKNKDFMFPSTVPLESETHGG 496
            :...| |.|||||.::.||||||||    ...|.  |.|:..::..::::...:.||||||||||
Zfish   405 LAPKQ-AEDDLPYTSILYANGPGYD----HVNGT--RGNVSVLDYYDEEYKQQAAVPLESETHGG 462

  Fly   497 DDVAVFASGPYAQLFTGVFEQHFIPHALGYASCLSDRNMC 536
            :|||::|.||.|.||.||.||:::.||:.||:||.....|
Zfish   463 EDVAIYAKGPMAHLFHGVKEQNYVAHAMAYAACLEPYTNC 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phu	NP_649897.4	PhoA	71..524	CDD:224699	202/467 (43%)
		alkPPc	93..530	CDD:214515	197/451 (44%)
alpi.1	NP_001014375.1	PhoA	46..493	CDD:224699	202/466 (43%)
		Alk_phosphatase	61..496	CDD:278666	198/452 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593231
Domainoid	1	1.000	363	1.000	Domainoid score	I896
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	383	1.000	Inparanoid score	I2001
OMA	1	1.010	-	-		QHG48882
OrthoDB	1	1.010	-	-		D216917at33208
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	1	1.000	-	-		mtm6481
orthoMCL	1	0.900	-	-		OOG6_100381
Panther	1	1.100	-	-	O	PTHR11596
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X159
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.910