DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment phu and Alp13

DIOPT Version :9

Sequence 1:	NP_649897.4	Gene:	phu / 41135	FlyBaseID:	FBgn0043791	Length:	546	Species:	Drosophila melanogaster
Sequence 2:	NP_649978.2	Gene:	Alp13 / 41236	FlyBaseID:	FBgn0037786	Length:	479	Species:	Drosophila melanogaster

Alignment Length:	501	Identity:	115/501 - (22%)
Similarity:	196/501 - (39%)	Gaps:	129/501 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 EYWQGLAAQT--------LDQQLESKLRLNTQLARNVMLFIGDGMS--------IPTITAGRVYL 115
            :||:...|.:        :|:..|:....:....:||.:|:..|:.        .||..|.|
  Fly    58 DYWKDKVATSQKIWYDKGIDELNEALRPQDLTYPKNVRIFVIQGIDGRDWAAFRFPTSDASR--- 119

  Fly   116 GGEEKQFAFEQFPYVGLSKTYCANMQVADSACTATAYLGGVKANYGTIGVSAAVQFKDCQAQAQA 180
              ....|.:::||::...|..|:.......|..:.|...|:..:      ......:||.....|
  Fly   120 --GNTNFIWDRFPHLARLKNSCSQQFPCQVASVSRALWLGIPLD------KVPDNQQDCGRLFNA 176

  Fly   181 AHHVSSIAAWAQKQGMATGLVTTTSVTHASPAGVYAHLANRNWENDAEVVGDNGDPDLCPDAAAQ 245
            .....||...||..|:.||.|||..:|  .|.|.....||.|:|.| |.:..|.....|.|.|.|
  Fly   177 TQGPISILRQAQLAGLRTGFVTTQRIT--GPTGAALGNANGNFECD-ESMPLNSIKSGCQDIAQQ 238

  Fly   246 LINSPVGQKLNVIMGGGRENFLPKGVTDSSGAPGRRL-----DGRNLIDEWKNQHTNSAQ----- 300
            ||:...|:.|||::||||: .|...|.::...|...:     |||||:.:|:||....::
  Fly   239 LISDETGKFLNVLIGGGRQ-MLSSLVPNTKYDPVDEMLCESNDGRNLLKDWRNQKLKESKINRII 302

  Fly   301 --YVENRRELLNL-SNHTSRVLGLFAPYHMAYHLDASPAEQPTLEEMVQSAMEILERQSAGRGYF 362
              .::.|.||.:| |:....::|:.|...:     :..::.|:|:.||..::.:|.:..  :||.
  Fly   303 FDLIQRRDELESLNSSSFDYLMGVMANGDL-----SGNSKAPSLKLMVDKSLNVLTKYK--QGYL 360

  Fly   363 LFVEGGRIDHGHHDTLALRAIDETAEFDKAVRFARSHTSTDD-TLIVVS-----------SDHSH 415
            |.|| ..|..|......|:.:::|        ....|...|. ||::::           |:.:.
  Fly   361 LIVE-QFIPSGIDKREQLQLLNDT--------LVNLHKDQDTLTLVLMTNAIYPKPSLDVSEETE 416

  Fly   416 TMSLAGYSSRKNDIFGINDGQLAADDLPYATLSYANGPGYDSNYLREGGAVRRKNLRAINMKNKD 480
            |:||.      .:||...:.::                              :|.|.
  Fly   417 TISLL------PEIFNEAESEI------------------------------QKRLH-------- 437

  Fly   481 FMFPSTVPLESETHGGDDVAVFASGPYAQLFTGVFEQHFIPHALGY 526
                 .:|.||        .:||.||.:.:|.||.::.|:.||:.:
  Fly   438 -----QMPSES--------LLFAQGPKSSIFQGVRKETFLAHAISH 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phu	NP_649897.4	PhoA	71..524	CDD:224699	112/493 (23%)
phu	NP_649897.4	alkPPc	93..530	CDD:214515	110/467 (24%)
Alp13	NP_649978.2	ALP_like	127..472	CDD:304875	101/427 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466687
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1785
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D216917at33208
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11596
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850