DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment phu and SPBC14F5.13c

DIOPT Version :9

Sequence 1:	NP_649897.4	Gene:	phu / 41135	FlyBaseID:	FBgn0043791	Length:	546	Species:	Drosophila melanogaster
Sequence 2:	NP_596739.1	Gene:	SPBC14F5.13c / 2539926	PomBaseID:	SPBC14F5.13c	Length:	532	Species:	Schizosaccharomyces pombe

Alignment Length:	461	Identity:	120/461 - (26%)
Similarity:	196/461 - (42%)	Gaps:	83/461 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 VMLFIGDGMSIPTITAGRVYL----GGEEKQFAFEQFPYVGLSKTYCANMQVADSACTATAYLGG 155
            |::.:.|||...:::..|.::    ..|..:...::. .:|.|:|..::..:.|||..|||:...
pombe    62 VIMMVSDGMGPGSLSMTRSFVETLNDKEGYRLPLDEH-LIGSSRTRSSSSLITDSAAGATAFSCA 125

  Fly   156 VKANYGTIGVSAAVQFKDCQAQAQAAHHVSSIAAWAQKQGMATGLVTTTSVTHASPAGVYAHLAN 220
            .|...|.:||  ....|.|          .:|...|::.|..||:|.|:.||.|:||...||.||
pombe   126 NKTYNGAVGV--LDNEKPC----------GTILEAAKEAGYLTGIVVTSRVTDATPASFSAHAAN 178

  Fly   221 RNWENDAEVVGDNGDPDLCPDAAAQLINSPVGQKLNVIMGGGRENFLPKGVTDSSGAPGRRLDGR 285
            |..:            ||.  |..|:...|:|:.::::.|||..:||||....|.     |.|..
pombe   179 RFMQ------------DLI--AEYQVGMGPLGRSVDLLFGGGLCSFLPKSTYRSC-----RSDNL 224

  Fly   286 NLIDEWKNQHTNSAQYVENRRELLNLSNHTSRVLGLFAPYHMAYHLDASPAEQPTLEEMVQSAME 350
            :|:...:.:  ...|.:.||.:...|||....:||||:.||::|.:|..|..||.|.|||::|::
pombe   225 DLLKYARKK--EGFQILLNRTDFDELSNAQLPLLGLFSDYHLSYDIDYQPEVQPKLSEMVETALD 287

  Fly   351 IL---ERQSAGRGYFLFVEGGRIDHGHHDTLALRAIDETAEFDKAVRFARSHTSTDDTLIVVSSD 412
            :|   ..:...:|:||.:||.|||...|:...:..:.|..|:::|...|.:....:...::.:||
pombe   288 VLLNATNEDTSKGFFLLIEGSRIDMASHNNDPIAHVYEVMEYNRAFEIASAFVEKNGGSLISTSD 352

  Fly   413 HS---------------------HTMSLAGYSSR--KNDIFGINDGQLAADDLPYA---TLSYAN 451
            |.                     ..:|||.:|..  .:.|...|...|    |||.   .|....
pombe   353 HETGGLTVGRQVSKKYPEYLWKPQVLSLALHSIEYLASAIVNHNQNTL----LPYIEQFVLPAIG 413

  Fly   452 GPGYDSNYLREGGAVRRKNLRAINMKNKDFMFPSTVPLESE----THG--GDDVAVFASGPYAQL 510
            .|..:...:.:....|......||      :....|.:|::    |||  ..||.|:..|...:.
pombe   414 IPDPNPKQIHDIYVARHNIFNLIN------VLSDIVSVEAQIGWTTHGHTAVDVNVYGVGEVTEH 472

  Fly   511 FTGVFE 516
            ..|..|
pombe   473 LRGNME 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phu	NP_649897.4	PhoA	71..524	CDD:224699	120/461 (26%)
phu	NP_649897.4	alkPPc	93..530	CDD:214515	120/461 (26%)
SPBC14F5.13c	NP_596739.1	PhoA	3..495	CDD:224699	120/461 (26%)
SPBC14F5.13c	NP_596739.1	ALP_like	60..487	CDD:304875	120/461 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	124	1.000	Domainoid score	I1405
eggNOG	1	0.900	-	-		E1_COG1785
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	124	1.000	Inparanoid score	I1462
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	1	1.000	-	-		otm46986
orthoMCL	1	0.900	-	-		OOG6_100381
Panther	1	1.100	-	-	O	PTHR11596
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X159
TreeFam	0	0.000	Not matched by this tool.
	10	9.860