DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment phu and arnt2

DIOPT Version :9

Sequence 1:	NP_649897.4	Gene:	phu / 41135	FlyBaseID:	FBgn0043791	Length:	546	Species:	Drosophila melanogaster
Sequence 2:	XP_012813827.1	Gene:	arnt2 / 100101693	XenbaseID:	XB-GENE-487404	Length:	723	Species:	Xenopus tropicalis

Alignment Length:	276	Identity:	61/276 - (22%)
Similarity:	99/276 - (35%)	Gaps:	91/276 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 AERRMHPVFSLM----------GTGSNPIGGGRYKRAMPQIVFDAVRSEERYAEYWQGLAAQTLD 78
            ||..:||..||.          ...:|...||:.....|..:|...| :.|:||.:.|:.|.  :
Frog   453 AELEVHPRDSLSSYDLSQVPVPNLAANVHEGGKSVVDKPDPIFSQDR-DPRFAEMFAGITAS--E 514

  Fly    79 QQLESKLRLNTQ-----------------LARNVMLFIG---------DGMSIPTIT----AGRV 113
            :::.|.....||                 .:.:|:...|         .|.::..|:    ||:|
Frog   515 KKMLSASGSGTQQLYSTGSPFQPGHSGKSFSSSVVHVTGVNEIQSPSATGQNLTQISRQMNAGQV 579

  Fly   114 YLGG----EEKQFAF-----EQFPY-VGLSKTYCANMQV-------ADSACTATAY--LGGVKAN 159
            :.|.    :.:|.|.     :..|: :|.|.||.::...       |.|:.:..||  |||..|.
Frog   580 WTGSRPPFQGQQIASQTSKPQSSPFGIGTSHTYTSDPSTYSPLSSPATSSPSGNAYSSLGGRSAA 644

  Fly   160 YGTIGVSAAVQFKDCQAQAQAAHHVSSIAAWAQKQGMATGLVTTTSVTHASPAGVYAHLANRNWE 224
            :...|.|::      |.|.:|:.      .|:|.|.......::....|..||
Frog   645 FTETGQSSS------QFQGRASE------VWSQWQSQHHNQPSSEQHPHQQPA------------ 685

  Fly   225 NDAEVVGD----NGDP 236
             .|||..|    :|||
Frog   686 -QAEVFQDMLPMSGDP 700

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phu	NP_649897.4	PhoA	71..524	CDD:224699	46/219 (21%)
phu	NP_649897.4	alkPPc	93..530	CDD:214515	41/180 (23%)
arnt2	XP_012813827.1	HLH	72..124	CDD:278439
		PAS	144..250	CDD:279347
		PAS	147..206	CDD:214512
		PAS_11	343..443	CDD:291273
		PAS	343..439	CDD:238075
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1785
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900