Protein Alignment CG16779 and LOC3290546

DIOPT Version :10

• Sequence 1: NP_649896.2
• Gene: CG16779 / 41134
• FlyBaseID: FBgn0037698
• Length: 2005
• Species: Drosophila melanogaster
• Sequence 2: XP_061503773.1
• Gene: LOC3290546 / 3290546
• VectorBaseID: AGAMI1_005125
• Length: 1930
• Species: Anopheles gambiae
• Alignment Length: 2303
• Identity: 781/2303 - (33%)
• Similarity: 1055/2303 - (45%)
• Gaps: 737/2303 - (32%)

  Fly     1 MAAINTVPKSIHLPLTTLSSAPRVLMCSASVGTEGSVTLQLRDANALEAAATKTATAAAAAAAAA 65
            |||:|:|..||.|||..| :.|||||||||:|.|||||||||:|
Mosquito     1 MAAVNSVQNSIRLPLAGL-APPRVLMCSASMGAEGSVTLQLREA--------------------- 43

  Fly    66 AATSTTSPNGVAGAPASTLENALTIGYPDPEMLADVLGTIQTAS--------------LKNNNSI 116
                ..:|:.     |.:|:.|||||||||:||||:|||.|.||              |:::|..
Mosquito    44 ----VQAPDA-----AGSLDGALTIGYPDPDMLADMLGTFQGASTGASGDPDAGSFELLQDSNGS 99

  Fly   117 TAA-------------------TSSNSSTKSTSSNHLTNPNKITIK-----RRSVHSVSTSTNSS 157
            .|.                   |.:||| .|:|||..|....:|||     :.:....|.:||..
Mosquito   100 PAGATLRTSAAEQLEQLAGAILTKANSS-GSSSSNVTTGATTVTIKTEPGPKSTAEKTSITTNLH 163

  Fly   158 SIS-SCSSSSSSSNSGKSNTSYIKNCLIRSSSCSNTVTNVTTLAQIMSNSSTSSAASLLNQHNNN 221
            ... :.:||..|||...|:|:.:.              :.||:..:.|:...|
Mosquito   164 PTGLTPTSSIGSSNLSPSSTAILH--------------HGTTMVTVKSSPGGS------------ 202

  Fly   222 SNCSNSSNFSTASSVGSSI--SVGSNSSSSNCSNGSNSNSNDSNSSSGGGHRLSFKGTGRHVPAS 284
                 ....:||:|..|.|  :||...::|....|.:|:|                       ||
Mosquito   203 -----GGTIATAASPTSLILTTVGRAETASGGFGGGSSSS-----------------------AS 239

  Fly   285 GLSSSAASTNTNGTVSGIGGIISVEAPRKNRPKLSSPTRHGPQQCQICCKIFGNASALAKHKLTH 349
            ...|:|||.   .::||:.        :|.|||..|||||||||||:|.|:||||||||||||||
Mosquito   240 SSPSAAASP---VSLSGLA--------KKPRPKTVSPTRHGPQQCQVCSKVFGNASALAKHKLTH 293

  Fly   350 SDERKYICALCSKAFKRQDHLNGHMMTHRNKKPYECKADGCGKSYCDARSLRRHSENHHAGGAAT 414
            ||||||:|.:|||||||||||||||:||||||||||||||||||||||||||||:||||
Mosquito   294 SDERKYVCGMCSKAFKRQDHLNGHMLTHRNKKPYECKADGCGKSYCDARSLRRHTENHH------ 352

  Fly   415 PTTSQSLSPTASSSGTSNSSGAGAATS----SLSLSPATASGDASSPDGATCIRTYISTGSSVV- 474
                 |....|:||||: |.|.|.:.:    .|||||||||||||||.|||.::...:|||...
Mosquito   353 -----SALGLANSSGTA-SPGPGGSNAGPPGGLSLSPATASGDASSPHGATLVQYTTTTGSGTPG 411

  Fly   475 DAATGIALSDEQIKAMNLPIKTGVTLLSPTTSTSSNASSSASSASSSLSATGSLPGSGSGSGSVS 539
            .:::..:||                      |:||::|||:||:|||.|::|::..|.|...|.|
Mosquito   412 SSSSNCSLS----------------------SSSSSSSSSSSSSSSSSSSSGNVSDSSSSCKSPS 454

  Fly   540 -MAPSPSSGSVITACSPTITLSDGMSLEGEGLTREQLDLISKIMQQTKQTSAQVTVSSPTSVSSY 603
             .:|:|.:|:                   |||||:||||||:|||||||.:|....::..:.::.
Mosquito   455 PSSPAPGAGN-------------------EGLTRQQLDLISQIMQQTKQANAAAAAAAAAAATTT 500

  Fly   604 KINTNS---SPSQN---RPRTWNMQL--------------------------------------- 623
            ..|.:|   |.||.   |||||||||
Mosquito   501 TTNGSSSVQSTSQKVPVRPRTWNMQLQLSQNKLSASTTVAATTAPTVVSAVPVPSMAVTATTTLS 565

  Fly   624 -----------------------LNSAQN-------------VTVTVEDNSELVTPSSNSPVEVK 652
                                   ::.|.|             .|:||..:|...|.|.::...|.
Mosquito   566 ASNSGATIVHQNGGTLSGNGSSIISKATNAGSASADPNGPVTATLTVSSSSAASTSSLSAVSAVS 630

  Fly   653 EEELSSQLVG---------------------------TMNPHLLNIVKLD-KPVECNLCHRKFKN 689
            ...|::...|                           |.........||: ||||||||||||||
Mosquito   631 ATSLTAGTAGPGSGSSSAAAAAAAATQQPATGTTATTTTTTTTTTATKLEQKPVECNLCHRKFKN 695

  Fly   690 IPALNGHMRLHGGYYKKDPETKRSEKKDSSGPPLQTASIGVRALIEEKIISKR-KD----MTKGS 749
            ||||||||||||||:|||.|.|:.:||:::||||||||:|||||||||||:|| ||    :.|||
Mosquito   696 IPALNGHMRLHGGYFKKDSEAKKCDKKENTGPPLQTASVGVRALIEEKIINKRSKDLKNLLLKGS 760

  Fly   750 FVVPAPPHSSGTTTTLRRSISDLESFLNPKTSSSSHTQTMTTTTGTTTAVLPAATTIKSSNGLSI 814
            |||||||      .|.||.|...|:||:.|.|    |..:.:|:..||.::..||....:..||:
Mosquito   761 FVVPAPP------LTARRLIDANEAFLSSKPS----TVAIVSTSNGTTQIINTATLHSKATVLSV 815

  Fly   815 QQIGLPQSIEIFSGGQKQAKTLNLGSGTNTITITTNNVPTTTTMSALTALKAGGTISGISTA-TN 878
            .....|                            :||..|:||::...      ||:|:..| ..
Mosquito   816 SSAPPP----------------------------SNNTTTSTTLAPSI------TINGLGAAGAA 846

  Fly   879 TDPKDSTLIELLKRGTRIAVTSKKNQSHGQTGSSTMMSSSGAAT-NAVGAVTELTTIGAGGGVQT 942
            |:.||:||||||||||::||  |:..:.|.  |||::|....|| |.  .||.::|..:     |
Mosquito   847 TELKDATLIELLKRGTKVAV--KRAMASGD--SSTVLSLQPQATPNP--TVTVVSTASS-----T 900

  Fly   943 VGRQIITN-NNRTVIIPSDVQVVSTKSKLSSLSSLVKCNMTNSGTSSSGNLSLADG------TPL 1000
            ...|::|: |.||      :.||.|...||:.::..|    .||.:.:|...||:.      |||
Mosquito   901 NPAQLLTSANTRT------LTVVPTGPTLSTSTTTGK----QSGQTIAGPTLLANATASTEPTPL 955

  Fly  1001 SLTIASNQELTGGGGNSSGSGSVITSGGGGVYTVTYTSDGTDLFDDAEVYNVSDTEMLLQTVDSM 1065
            ||||:.....|                .|.|:|:.|::|    |.|.:||:||||.||||.||.:
Mosquito   956 SLTISQAPATT----------------PGDVFTLAYSTD----FGDGDVYSVSDTAMLLQAVDPI 1000

  Fly  1066 ELLNDEEIKSEHSEDFALLSEAGDSAHTQLVKLEPESGQANSGSGSVSGANTTPLP----TFQQF 1126
            :||:|.. .:|..::.| ||:.|..           |.|..:.|..:.....:|||    .|...
Mosquito  1001 QLLHDSN-SAEPLDEIA-LSDYGSI-----------SDQGFTPSRQIQAVLDSPLPEGLAEFSAL 1052

  Fly  1127 HSKELIM-------------QNSSQIQAIASMRGSGGGVLASPLHSPLAYPTPPSSHENMAQSSP 1178
            |.|:..:             .:||.....|.::.|..|...|||.|||||||||:|||.:||:||
Mosquito  1053 HGKDFSVLYGGTGAPSSEPNGSSSTTNTSALLQSSPSGAHLSPLPSPLAYPTPPASHEAVAQASP 1117

  Fly  1179 FIEDAAAQFVDASNTFFGDKTDFSHI----YFKTD--EGEATIEQLNEHDNEKILKLKSVLEDSS 1237
            |::| :..|.|| .:||.||......    :|||:  :|:.     ...::.|||.||..|.|.:
Mosquito  1118 FLDD-SRHFTDA-GSFFDDKRSAQSFLDDGFFKTEPKDGDC-----KASESAKILALKHELLDEN 1175

  Fly  1238 FD---------------PSIKVEDLLNGTDDDTECDLREFAETNLSFLDEDQEFLNDSRNATSPL 1287
            .|               ...|.||   |...:::......::.||.|||:.|.|:.::|||:|||
Mosquito  1176 HDLFRANKHHLLDEHCSELFKTED---GFFAESKPSADGTSKMNLDFLDDAQVFIEETRNASSPL 1237

  Fly  1288 SESFFTSGIGSAEDVKQVLREVLP-DENMQLQLSSEQQGENIIDLYYLPGL-GLQSQMMPNSEDP 1350
            |.:||::.:.||.:||:.|.|||| |::..:.:|     |..||||||.|| .|||||||||:||
Mosquito  1238 SNAFFSATMSSAAEVKEALDEVLPNDDDDDIGVS-----EGDIDLYYLNGLSSLQSQMMPNSDDP 1297

  Fly  1351 LLSSSPREFGQQRQQ--LPMQTTNMQQPMEQTLQDNNNIYQQQEQQQEQHQQQQSQQEQPPQQEQ 1413
            ||||||::|..::.|  |..|:...||         ..:.|.|:|.|:|.||||.||:|..||:|
Mosquito  1298 LLSSSPKDFAHRQHQKFLFEQSQAAQQ---------QQLAQHQQQLQQQQQQQQQQQQQLQQQQQ 1353

  Fly  1414 QQ--------QHHQQLLMPQQPLNQTESLPAVGQQQGDF-----MLPLVGGHGFTQVTSQTQYID 1465
            ||        .||      ..|.:..:|.|:..:..|.|     ..||         |.||..:.
Mosquito  1354 QQAGVTTTTTNHH------CMPPSAKKSKPSDVEASGTFGADASKAPL---------TVQTDPMP 1403

  Fly  1466 NSQGGMGMQPLNSLLQPLLYGGATTSNGNASAGGNESLLTTDCQMNANQGQIDTGLMFACGNTTT 1530
            .....:.:.|                          |.|::                .:|.::::
Mosquito  1404 KDADSVFLSP--------------------------SSLSS----------------HSCSSSSS 1426

  Fly  1531 MANKSLAAIVSNPPSVANLQPLSNQTNSIL---KRRLRSNAPQETHKFSKFHTLSPHRSKLRKPS 1592
            .::.||:::.|.....|.|.........::   ||...|.:.|.....|...|...|.:..|||:
Mosquito  1427 SSSLSLSSVASPRLQHALLGSAHPAAGGVVWPRKRSQTSASSQSPSANSAAGTTPSHPAGQRKPT 1491

  Fly  1593 ---------------RTHYTPAPILNPDRKGT-GLYCNVRKQLGQGLFDAFDDDFGDSVGLVDFS 1641
                           ..||||||:|||:|.|| |||.:.   .|..:.:...|...||...: ||
Mosquito  1492 VYLSKLRRSTAALLPALHYTPAPMLNPERCGTAGLYASA---AGGSVVEPDLDSTMDSTSDI-FS 1552

  Fly  1642 D-----ESKVNLGSTYQAQIPSCRPLEEALRDSPG---AEMMWNPEVQEDEKILMRYIDLSKSSA 1698
            :     ..::|||..|||.:|.|.....|....||   .:.:|:|.:..:::.|.|:|:|::|||
Mosquito  1553 EPPLPIRPRINLGPDYQATLPDCARPAYAAPFQPGVPPVQRLWDPALAPNDRQLQRFIELARSSA 1617

  Fly  1699 VPMGSHSEEVALQTLLRAKGNSAAAVLSLLQTQSGAFQMKWTAYELEQFLRGLEKNGKDFGKIAS 1763
            .|:|.||||.||:.||.|.|....|:|.:||........:|||.|:||.::|||:.||||.:||.
Mosquito  1618 APLGCHSEENALRALLEANGEIHQAILGMLQGPPATIHRRWTADEIEQLIQGLEEYGKDFHRIAR 1682

  Fly  1764 E-LQTKSSGECVQMYYFWKKLCVDY-KVT------------HLKMEPV---VVIAPAVE------ 1805
            : |..||:|:|||||||||||.:|| |.|            |..:.|.   ....|.||
Mosquito  1683 DLLPGKSTGDCVQMYYFWKKLGIDYGKGTTALAAGPKYGGLHGALSPTPSPPAPTPPVEDLLLDH 1747

  Fly  1806 ----------------------------------------KPYVCEIADCSASFSSKAALHGHVR 1830
                                                    :|:|||:.|||||||||||||||:|
Mosquito  1748 LDYTASASAGATMPRGQQAGGSNSGNLQPNGHGSSTASDVRPHVCEVPDCSASFSSKAALHGHIR 1812

  Fly  1831 IHAYGRSASSNTTNNNSSSSNTGSSSNVQHAAASSASSGGNNNNSSSYACATLSGSNGSSNNAST 1895
            ||..||:.|  |..|.:..|..|:..|..|
Mosquito  1813 IHCIGRNHS--TVQNGNFLSAAGNPINPNH----------------------------------- 1840

  Fly  1896 NVAGAVATHSSNMAQNGSNCSGHANAAIATSALSTTPKLEAGMGNTTNIPIAKEGEFPCKVCGKV 1960
                                                              |..:.::||||||||
Mosquito  1841 --------------------------------------------------IPTKDDYPCKVCGKV 1855

  Fly  1961 FNKVKSRSAHMKTHRVQE-PDQ-KHQLQ 1986
            ||||||||||||:||.|: .|| :||||
Mosquito  1856 FNKVKSRSAHMKSHRPQDASDQLQHQLQ 1883

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16779	NP_649896.2	C2H2 Zn finger	329..349	CDD:275368	16/19 (84%)
		zf-C2H2	355..377	CDD:395048	17/21 (81%)
		C2H2 Zn finger	357..377	CDD:275368	16/19 (84%)
		C2H2 Zn finger	385..407	CDD:275368	20/21 (95%)
		ELM2	1646..1696	CDD:460214	17/52 (33%)
		SANT	1738..1782	CDD:473887	27/44 (61%)
		C2H2 Zn finger	1810..1832	CDD:275368	18/21 (86%)
		zf-C2H2_6	1952..1975	CDD:433576	20/22 (91%)
		C2H2 Zn finger	1954..1974	CDD:275368	19/19 (100%)
LOC3290546	XP_061503773.1	None