Protein Alignment CG16779 and Mideas

DIOPT Version :10

• Sequence 1: NP_649896.2
• Gene: CG16779 / 41134
• FlyBaseID: FBgn0037698
• Length: 2005
• Species: Drosophila melanogaster
• Sequence 2: NP_001156973.1
• Gene: Mideas / 238317
• MGIID: 2685106
• Length: 1089
• Species: Mus musculus
• Alignment Length: 984
• Identity: 205/984 - (20%)
• Similarity: 308/984 - (31%)
• Gaps: 393/984 - (39%)

  Fly  1335 PGLGLQSQMMPNSEDPLLSSSPR-EFGQQRQQLPMQTTN-MQQPMEQTL-----------QDNNN 1386
            || |.|.....|:..|::....: |.|  |.|.|:.:.: .::|..|||           |.|..
Mouse   170 PG-GPQLDHYGNAVQPMVPQKVQLEVG--RPQAPLNSFHAAKKPPNQTLPLQPFQLAFGHQVNRQ 231

  Fly  1387 IYQQ-------------QEQQQEQH-----QQQQSQQEQPPQQEQQQQHHQQLLMPQQPLNQTE- 1432
            :::|             |:|||:|.     |.|..:...|..|...|||....|.|..||.||.
Mouse   232 VFRQGPQPSNPTASFPPQKQQQQQQPAALPQMQLFENYYPMHQLPSQQHQDFGLAPGGPLGQTHL 296

  Fly  1433 -----------------------------SLPAVGQQQGDF-----------MLPLVGGHGFTQV 1457
                                         |.|.:.|.|..|           :||
Mouse   297 AHRSMAPYPFSHNPDMNPELRKALLQDPASQPVLPQPQMAFPRRSRRLSKEGILP---------- 351

  Fly  1458 TSQTQYIDNSQGGMGMQPLN-----------SLLQP------------------------LLYGG 1487
                   .||..|.|.||..           ||.||                        |..|.
Mouse   352 -------SNSLDGAGTQPGQEPASNLFLHHWSLPQPPPGTLGQPHSEALGFPLELRESQMLADGD 409

  Fly  1488 ATTSNG---NASAGGNESLLTT----DCQMNANQGQI-----------DTGLMFACGNTTTMAN- 1533
            ....||   ...|.|||.::..    ||......|.|           :..|:........:|:
Mouse   410 RLAPNGREREPPAMGNEEVMRAGGLGDCGQMIRSGVIQSTKRRRRVSQEANLLTLAQKAVELASM 474

  Fly  1534 ----------KSLAAIVS------------------------------------NPPSVANL--- 1549
                      ||:.|..|                                    .|..||.:
Mouse   475 QDANGSEEKRKSVLATTSRCGVEFSEPALAAKRAREESGMVPLIIPVSVPVRTVGPTEVAQVGGA 539

  Fly  1550 ---------QPLSNQTNSILKRRLRSNAP-----------------QETHKFSK----------- 1577
                     .|..::.:.|:.||..:..|                 :.:.:..|
Mouse   540 DEDGTGLEQYPTEHKPSVIVTRRRSTRVPGTDAAAQAEDLNVKLEGEPSMRKPKQRPRPEPLIIP 604

  Fly  1578 -----------FHTLSPHRSKLRKPSR--TH----------YTPAPILNPDRKGTGLYCN----- 1614
                       :..::|::|.||.|.|  .|          |||.|||:|.|:|:|||.|
Mouse   605 TKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFEPPPYTPPPILSPVREGSGLYFNAIIST 669

  Fly  1615 ---------VRKQLGQGLFDAFDDD--------FGDSVGLVDFSDESKVNLGSTYQAQIPSCRPL 1662
                     ..|...:.|..:...:        .|::..:   |.|.::|:|:.:||:||..|..
Mouse   670 SNIPAPPPITPKSAHRTLLRSNSSEVTPPVLSVMGEATPV---SIEPRINVGTRFQAEIPMMRDR 731

  Fly  1663 EEALRDSPGAEMMWNP-EVQEDEKILMRYID----LSKSSAVPMGSHSEEVALQTLLRAKGNSAA 1722
            ..|..|...|:::|.| |..|......|.:|    .:.||..|....::|:||..|..::|:...
Mouse   732 ALAAFDPHKADLVWQPWEHLESSWEKQRQVDDLLTAACSSIFPGAGTNQELALHYLHESRGDILE 796

  Fly  1723 AVLSLLQTQ--------------SGAFQMKWTAYELEQFLRGLEKNGKDFGKIASELQTKSSGEC 1773
            |:..||..:              :|:.|  |...|.:.|.:|:....|||..:...:|||:..:|
Mouse   797 ALNKLLLRKPLRPHNHPLATYHYTGSDQ--WKTAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQC 859

  Fly  1774 VQMYYFWKK--------------------------LCVDYKVTHL--KMEPVVVIAPAVEKPYVC 1810
            |:.||.:||                          :.||.|.:..  ::.|     |..|.|
Mouse   860 VEFYYTYKKQVKIGRNGTLTFGDLDIGDEKSGQEEVEVDVKTSQKFPRVPP-----PRRESP--- 916

  Fly  1811 EIADCSASFSSKAALHGHVRIHAYGRSASSNTTNNNSSSSNTGSSSNVQHAAASSASSGGNNNNS 1875
                      |:..|.....:....:.......:..............:.|||..|:.
Mouse   917 ----------SEERLEPKREVTEPRKEGEEEVPDTQEKGEQEEGRERCRRAAAVKATQ------- 964

  Fly  1876 SSYACATLSGSNGSSNNA------STNVAGAVATHSSNMAQNGSNCSGHANAAIATSALSTTPKL 1934
                  ||. :|.::|:.      ..|..|:....:|...:.|   .|.:..|:.    .|..|.
Mouse   965 ------TLQ-ANEAANDVLILRSHEPNAPGSAGIQTSEKPREG---PGKSRRALP----FTEKKK 1015

  Fly  1935 EAGMGNTTNIPIAKEGEFPCKVCGKVFNKVKSRSAHMKTHRVQEPD--------------QKHQ- 1984
            :|...|.|.   .:|..||||.||:||.||||||||||:|..||..              ..||
Mouse  1016 KAEAFNKTQ---NQENTFPCKKCGRVFYKVKSRSAHMKSHAEQEKKAAALRLKEKEAAAAAAHQQ 1077

  Fly  1985 -LQNQAGAG 1992
             |:.::|.|
Mouse  1078 ALREESGEG 1086

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16779	NP_649896.2	C2H2 Zn finger	329..349	CDD:275368
		zf-C2H2	355..377	CDD:395048
		C2H2 Zn finger	357..377	CDD:275368
		C2H2 Zn finger	385..407	CDD:275368
		ELM2	1646..1696	CDD:460214	16/54 (30%)
		SANT	1738..1782	CDD:473887	14/43 (33%)
		C2H2 Zn finger	1810..1832	CDD:275368	2/21 (10%)
		zf-C2H2_6	1952..1975	CDD:433576	18/22 (82%)
		C2H2 Zn finger	1954..1974	CDD:275368	16/19 (84%)
Mideas	NP_001156973.1	ELM2	715..770	CDD:460214	16/54 (30%)
		SANT	824..868	CDD:473887	15/45 (33%)
		PTZ00121	<887..>1068	CDD:173412	50/222 (23%)