Protein Alignment CG16779 and Trerf1

DIOPT Version :10

• Sequence 1: NP_649896.2
• Gene: CG16779 / 41134
• FlyBaseID: FBgn0037698
• Length: 2005
• Species: Drosophila melanogaster
• Sequence 2: NP_001419746.1
• Gene: Trerf1 / 224829
• MGIID: 2442086
• Length: 1237
• Species: Mus musculus
• Alignment Length: 1309
• Identity: 277/1309 - (21%)
• Similarity: 426/1309 - (32%)
• Gaps: 505/1309 - (38%)

  Fly  1068 LNDEEI-KSEHSEDFALLSEAGDSAHTQLVKLEPESGQANSGSGSVSGA-----NTTPL-PTFQQ 1125
            :.|::: |:.|      :...|::...|...|...||..:|...::|||     ..:|: |.|.|
Mouse     1 MGDQQLYKTNH------VGHGGENLFYQQPPLGVHSGLGHSYGNTISGAGMDAPQASPISPHFPQ 59

  Fly  1126 ---------FHSKELIMQNSSQIQAIASMRGSGGGVLASPLHSPLAYPTPPSSHENMAQSSPF-I 1180
                     ..||.|...::|:.....|..|.|..|   .|.|.||       :.||...:|. :
Mouse    60 DTRDGLGLPIGSKNLGQMDTSRQGGWGSHAGPGNHV---QLRSNLA-------NSNMMWGTPTQV 114

  Fly  1181 EDA-AAQFVDASNTFFGDKTDFSHIYFKTDEGEATIEQLN----EHDNEKILKLKSVLEDSSFDP 1240
            |.| ..|:..:..:....:...|.:..|.|.........|    .::..::|..:|.:.|.:.|.
Mouse   115 EPADGYQYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGASDS 179

  Fly  1241 SIKVEDLLN---------------------------GTDDDTECDLREFAETNLSFLDEDQEFLN 1278
            :::  .||:                           |........:.:.|.....:.|..|....
Mouse   180 ALR--QLLSQKPVEPSASAIASRYQQVPQQPHPGFTGGLPKPALPVGQHAPQGHLYYDYQQPLAQ 242

  Fly  1279 DSRNATSPLSESFFTSGIGSAEDVKQVLREVLPDENMQ-LQLSSEQQGENIIDLYYLPGLGLQSQ 1342
            .|.....||......||........|...:..|.:... ||..|.|:              :|.|
Mouse   243 MSMQGGQPLQAPQVLSGHMQQLQQHQYYPQPPPQQQQAGLQRISVQE--------------MQQQ 293

  Fly  1343 MMPNSEDPLLSSSPREFGQQRQQLPMQTTNMQ-------QPMEQTLQDNNNIYQQQEQQQEQHQQ 1400
            ..|....|   |.|::  ||:.||..:.:::|       |||.|.|        |::||...|.|
Mouse   294 QQPQQIRP---SPPQQ--QQQLQLQQRQSSLQIPQYYQPQPMMQHL--------QEQQQPSMHLQ 345

  Fly  1401 QQSQQEQPPQQEQQQQHHQQLL----MPQ---QPLNQTESLP-------AVGQQQGDFML----- 1446
            ..|....|.|...:|.|..||:    |||   |...|..|.|       :..||:.|..|
Mouse   346 PPSYHRDPHQYTPEQAHAVQLIQLGSMPQYYYQEPQQAYSHPLYPQSHLSQHQQREDGQLKTYSS 410

  Fly  1447 -----PLVGGHG----------------FTQVTSQTQYID---------NSQGGMGMQPLN-SLL 1480
                 .::..||                .|:|||...:..         |:.|....||.: |.:
Mouse   411 DRQTPAMLSSHGDMGTSDTGVADPASSEMTRVTSTLPHQPLLSPSGIHLNNMGSQHQQPPSPSAM 475

  Fly  1481 QPLLYGGATTSNGNASAGGNESLLTTDCQMNANQGQIDTGLMFACGNTTTMA-----NKSLAAIV 1540
            .|.::    ..:|.|.:|..||        ::.|.:...|..|...|..|.:     .|||.|:.
Mouse   476 WPQMH----LPDGRAQSGSPES--------SSGQTKGVFGEQFDAKNKLTCSICLKEFKSLPALN 528

  Fly  1541 SN------------------------------------------------PPSVANLQPL----- 1552
            .:                                                ||....|.|:
Mouse   529 GHMRSHGGMRASPSLKQEEGEKAPPPQPQPQPQPQQPLPPPPPPPPPPQLPPEAERLTPMVMPVS 593

  Fly  1553 ----------SNQ--TNS---------------------ILKRRLRS--NAPQ------------ 1570
                      |:|  |||                     :|.|...|  ::||
Mouse   594 VPVKLIPPKPSSQGFTNSVAATPAARDKPASSMSDDEMPVLVRMTLSPPHSPQGAAPRAPAEIPR 658

  Fly  1571 -----------------ETHKF------------SKFHTLSP--------HRSKLRKP------- 1591
                             |..||            ...:|.:|        ::|:||.|
Mouse   659 KHPPIAAKVEEPLKNLPEKKKFRHRPEPLFIPPPPSSYTPNPTSYSGATLYQSQLRSPRILGDHL 723

  Fly  1592 --SRTH----YTPAPILNPDRKGTGLYCNVR-KQLGQGLF-------------------DAFDDD 1630
              ...|    |||.|:|:|.|:|:||:.||. ...|.|:.                   .:.|
Mouse   724 LLDPAHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGVHPQLPLTPLTPTPRVLLCRSSSID-- 786

  Fly  1631 FGDSVGL--------VDFSDESKVNLGSTYQAQIPSCRPLEEALRDSPGAEMMWNPEVQEDEKIL 1687
             |.:|.:        ||.  |.::|:|..:||:||..:.:....:|:..|.::|.|..:.:.:.|
Mouse   787 -GSNVTVTPGPGEQTVDV--EPRINIGLRFQAEIPELQDVSALAQDTHRATLVWKPWPELENQAL 848

  Fly  1688 MRYID----LSKSSAVPMGSHSEEVALQTLLRAKGNSAAAVLSLLQTQSGAFQM----------- 1737
            .:.::    |..|||:|.|..:.|.||.:|..|||:..|.:..||..:....:.
Mouse   849 QQQVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMATLEMLLLRKPVRLKCHPLANYHYAGS 913

  Fly  1738 -KWTAYELEQFLRGLEKNGKDFGKIASELQTKSSGECVQMYYFWKKL-------------CVDYK 1788
             |||:.|.:.|.:.|....|||..:...:::|:..:||:.||.|||:             .:|..
Mouse   914 DKWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRKHRTRLAEIIDDC 978

  Fly  1789 VTHLKME------------------------------PVVVIAPAVEKP-----------YVCEI 1812
            :|..:.|                              |...:||....|           ::||:
Mouse   979 MTSEEEEEAEEEEEDPEEDRKSIKEEESEVAKSPEPPPAPALAPTEGPPMQAVGQQPSGNFICEM 1043

  Fly  1813 ADCSAS------------FSSKAALHGHVRIHAYGRSASSNTTNNNSSSSNTGSSSNVQHAAASS 1865
            .:|.|.            |||:.||:||.|||
Mouse  1044 PNCGADCRCHVAPFLPQVFSSRQALNGHARIH--------------------------------- 1075

  Fly  1866 ASSGGNNNNSSSYACATLSGSNGSSNNASTNVAGAVATHSSNMAQNGSNCSGHANAAIATSALST 1930
               ||.|..:.:                    .||:   .|...:.|...||:.:...:.|. ||
Mouse  1076 ---GGTNQVAKT--------------------RGAI---PSGKQKPGGTQSGYCSVKSSPSH-ST 1113

  Fly  1931 TPKLEAGMGNTTNIPIAKEGEFPCKVCGKVFNKVKSRSAHMKTHRVQEPDQKHQLQNQAGAGLTT 1995
            |    :|..:.|.|       ||||.|||||.|:|||:|||||||.||..|:.:.|..|.|....
Mouse  1114 T----SGETDPTTI-------FPCKECGKVFFKIKSRNAHMKTHRQQEEQQRQKAQKAAFAAEMA 1167

  Fly  1996 VATSTITAP 2004
            ......|.|
Mouse  1168 ATIERTTGP 1176

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16779	NP_649896.2	C2H2 Zn finger	329..349	CDD:275368
		zf-C2H2	355..377	CDD:395048
		C2H2 Zn finger	357..377	CDD:275368
		C2H2 Zn finger	385..407	CDD:275368
		ELM2	1646..1696	CDD:460214	12/53 (23%)
		SANT	1738..1782	CDD:473887	15/43 (35%)
		C2H2 Zn finger	1810..1832	CDD:275368	12/33 (36%)
		zf-C2H2_6	1952..1975	CDD:433576	18/22 (82%)
		C2H2 Zn finger	1954..1974	CDD:275368	15/19 (79%)
Trerf1	NP_001419746.1	PAT1	<176..>399	CDD:401645	53/251 (21%)
		PRK10263	<322..>454	CDD:236669	34/139 (24%)
		zf-C2H2_6	514..534	CDD:433576	4/19 (21%)
		ELM2	807..861	CDD:460214	12/53 (23%)
		SANT	915..959	CDD:473887	15/43 (35%)
		zf-C2H2_6	1123..1146	CDD:433576	18/29 (62%)