DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstZ2 and GSTZ1

DIOPT Version :9

Sequence 1:	NP_649895.1	Gene:	GstZ2 / 41133	FlyBaseID:	FBgn0037697	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_001350632.1	Gene:	GSTZ1 / 2954	HGNCID:	4643	Length:	217	Species:	Homo sapiens

Alignment Length:	210	Identity:	125/210 - (59%)
Similarity:	155/210 - (73%)	Gaps:	0/210 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 QPILYSYWRSSCSWRVRIAMNLKEIPYDIKPISLIKSGGEQHCNEYREVNPMEQVPALQIDGHTL 79
            :||||||:|||||||||||:.||.|.|:..||:|||.||:|...:::.:|||:|||.|:|||.|:
Human     6 KPILYSYFRSSCSWRVRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVPTLKIDGITI 70

  Fly    80 IESVAIMHYLEETRPQRPLLPQDVHKRAKVREIVEIICSGIQPLQNLIVLIHVGEEKKKEWAQHW 144
            .:|:||:.||||.||...|||||..|||.||.|.::|..||||||||.||..||||.:..|||:.
Human    71 HQSLAIIEYLEEMRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQVGEEMQLTWAQNA 135

  Fly   145 ITRGFRAVEKALSTSAGKYCVGDEISMADCCLVPQVFNARRFHVDLRPYPIILRIDRELESNPAF 209
            ||.||.|:|:.|.::||.||||||::|||.||||||.||.||.|||.|||.|..|::.|....||
Human   136 ITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDLTPYPTISSINKRLLVLEAF 200

  Fly   210 RAAHPSNQPDCPPEL 224
            :.:||..|||.|.||
Human   201 QVSHPCRQPDTPTEL 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstZ2	NP_649895.1	GST_N_Zeta	16..90	CDD:239340	44/73 (60%)
		maiA	17..221	CDD:273527	121/203 (60%)
		GST_C_Zeta	104..217	CDD:198300	65/112 (58%)
GSTZ1	NP_001350632.1	maiA	8..212	CDD:273527	121/203 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143210
Domainoid	1	1.000	97	1.000	Domainoid score	I7276
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	253	1.000	Inparanoid score	I3208
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63171
OrthoDB	1	1.010	-	-		D1283865at2759
OrthoFinder	1	1.000	-	-		FOG0002989
OrthoInspector	1	1.000	-	-		otm40913
orthoMCL	1	0.900	-	-		OOG6_103004
Panther	1	1.100	-	-	LDO	PTHR42673
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1983
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.770