DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstZ1 and EEF1E1

DIOPT Version :9

Sequence 1:	NP_649894.1	Gene:	GstZ1 / 41132	FlyBaseID:	FBgn0037696	Length:	246	Species:	Drosophila melanogaster
Sequence 2:	NP_004271.1	Gene:	EEF1E1 / 9521	HGNCID:	3212	Length:	174	Species:	Homo sapiens

Alignment Length:	149	Identity:	33/149 - (22%)
Similarity:	61/149 - (40%)	Gaps:	27/149 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 SLLKTVSGHAYTDEYREVNPMQKVPSLKI-DGHTLCDSVAIIHYLEETRPQPALLPQDPVKRAKI 128
            |||:...|.:..::|......| :|.|:. :|.:|.....|..:|.:...:..||.....::|.:
Human     8 SLLEKSLGLSKGNKYSAQGERQ-IPVLQTNNGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKAIV 71

  Fly   129 REIVELICSGIQPLQNVSVLD-HIGKDQSLQWAQHWISRGFQGLEKVLSHSAGK-FCVGDELSMA 191
            ::.:|         ..|:.:| |..|:..     |.:      |:.:.|:...| :..|...::|
Human    72 QQWLE---------YRVTQVDGHSSKNDI-----HTL------LKDLNSYLEDKVYLTGYNFTLA 116

  Fly   192 DICLVPQVRNARRYKADLT 210
            ||.|   .....|:..|||
Human   117 DILL---YYGLHRFIVDLT 132

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstZ1	NP_649894.1	GST_N_Zeta	34..109	CDD:239340	11/44 (25%)
		maiA	35..240	CDD:273527	33/149 (22%)
		GST_C_Zeta	122..236	CDD:198300	19/91 (21%)
EEF1E1	NP_004271.1	N-terminal	2..56		12/48 (25%)
		Linker	57..63		2/5 (40%)
		C-terminal	64..152		19/92 (21%)
		GST_C_AIMP3	65..165	CDD:198338	19/91 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900