DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstZ1 and CAM1

DIOPT Version :9

Sequence 1:	NP_649894.1	Gene:	GstZ1 / 41132	FlyBaseID:	FBgn0037696	Length:	246	Species:	Drosophila melanogaster
Sequence 2:	NP_015277.1	Gene:	CAM1 / 856059	SGDID:	S000005969	Length:	415	Species:	Saccharomyces cerevisiae

Alignment Length:	232	Identity:	43/232 - (18%)
Similarity:	92/232 - (39%)	Gaps:	52/232 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 SWRVRVALAIKKIDYDIKPTSLLKTVSGHAYTDEYREVNPMQKVPS-LKIDGHTLCDSVAIIHYL 108
            :|..|..:...|:|        :|.|:..|..:::....|::|||: :...|:.|.:::||.:||
Yeast    14 TWVPRGLVKALKLD--------VKVVTPDAAAEQFARDFPLKKVPAFVGPKGYKLTEAMAINYYL 70

  Fly   109 ----EETRPQPALLPQDPVKRAKIR----------EIVELICSGIQPLQNVSVLDHIGKDQSLQW 159
                ::.:.:..||..|....|:.:          ::...|.:.|.||:..:..:....|.::
Yeast    71 VKLSQDDKMKTQLLGADDDLNAQAQIIRWQSLANSDLCIQIANTIVPLKGGAPYNKKSVDSAM-- 133

  Fly   160 AQHWISRGFQGLEKVLSHSAGK-----FCVGDELSMADICLVPQVRNARRYKADL------TPYP 213
                     ..::|::.....:     :...:.:|:||:......   .||...|      ..:|
Yeast   134 ---------DAVDKIVDIFENRLKNYTYLATENISLADLVAASIF---TRYFESLFGTEWRAQHP 186

  Fly   214 TIVRLNQELQE----LDVFKATHPSTQPDCPPEFAKK 246
            .|||....::.    .|.:|....:.:|..||:..|:
Yeast   187 AIVRWFNTVRASPFLKDEYKDFKFADKPLSPPQKKKE 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstZ1	NP_649894.1	GST_N_Zeta	34..109	CDD:239340	17/68 (25%)
		maiA	35..240	CDD:273527	40/224 (18%)
		GST_C_Zeta	122..236	CDD:198300	19/138 (14%)
CAM1	NP_015277.1	GST_N_EF1Bgamma	4..73	CDD:239342	17/66 (26%)
		GST_C_EF1Bgamma_like	92..214	CDD:198290	19/135 (14%)
		EF1G	255..359	CDD:395522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345120
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740