DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstZ1 and EEF1G

DIOPT Version :9

Sequence 1:	NP_649894.1	Gene:	GstZ1 / 41132	FlyBaseID:	FBgn0037696	Length:	246	Species:	Drosophila melanogaster
Sequence 2:	NP_001395.1	Gene:	EEF1G / 1937	HGNCID:	3213	Length:	437	Species:	Homo sapiens

Alignment Length:	240	Identity:	57/240 - (23%)
Similarity:	92/240 - (38%)	Gaps:	49/240 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LYSYWPSSCSWRVRVALAIKKIDYDIKPTSLLKTVSGHAY------TDEYREVNPMQKVPSLK-I 93
            ||:| |.  :||...||...:  |......:| :...|.:      |.|:....|..|||:.: .
Human     6 LYTY-PE--NWRAFKALIAAQ--YSGAQVRVL-SAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGD 64

  Fly    94 DGHTLCDSVAIIHYL--EETRPQPALLPQDPVKRAKIREIVELICSGIQPLQNVSVLDHIG---- 152
            ||..:.:|.||.:|:  ||.|      ...|...|::.:.|....|.|.|..:..|...:|
Human    65 DGFCVFESNAIAYYVSNEELR------GSTPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHH 123

  Fly   153 KDQSLQWAQHWISRGFQGLEKVLSHSAGKFCVGDELSMADICLV------------PQVR----N 201
            ..|:.:.|:..:.|....|:..|  ....|.||:.:::|||.:|            |..|    |
Human   124 NKQATENAKEEVRRILGLLDAYL--KTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPN 186

  Fly   202 ARRYKADLTPYPTI------VRLNQELQELDVFKATHPSTQPDCP 240
            ..|:.......|..      |:|.:::.:.|..|......:.|.|
Human   187 TNRWFLTCINQPQFRAVLGEVKLCEKMAQFDAKKFAETQPKKDTP 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstZ1	NP_649894.1	GST_N_Zeta	34..109	CDD:239340	23/81 (28%)
		maiA	35..240	CDD:273527	56/238 (24%)
		GST_C_Zeta	122..236	CDD:198300	29/139 (21%)
EEF1G	NP_001395.1	GST_N_EF1Bgamma	4..82	CDD:239342	23/81 (28%)
		GST_C_EF1Bgamma_like	91..213	CDD:198290	26/123 (21%)
		tolA	<212..>278	CDD:236545	4/20 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..268		2/11 (18%)
		EF1G	277..381	CDD:395522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810