Protein Alignment alpha-Man-IIa and man2c1

DIOPT Version :10

• Sequence 1: NP_001262413.1
• Gene: alpha-Man-IIa / 41126
• FlyBaseID: FBgn0011740
• Length: 1109
• Species: Drosophila melanogaster
• Sequence 2: XP_009296368.1
• Gene: man2c1 / 569595
• ZFINID: ZDB-GENE-101103-4
• Length: 1034
• Species: Danio rerio
• Alignment Length: 873
• Identity: 166/873 - (19%)
• Similarity: 274/873 - (31%)
• Gaps: 268/873 - (30%)

  Fly   140 NAHHKLKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYF---ARF 201
            |...:..|..:.|.|.|..|:..:||..:...:..:: .:|.:..|||..|..::...|   ..:
Zfish   256 NGESQHVVHAMGHCHIDSAWLWPYEETIRKCARSWVT-VIRLMEKNPEFVFTCSQAQQFQWVKSW 319

  Fly   202 YHDLGENKKLQMKSIVKNGQLEFVTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWA 266
            |..|..    ::|..::.||...|.|.||..|.......:::.|...||.:.|..........|.
Zfish   320 YPGLFS----EIKHFIQKGQFIPVGGTWVEMDGNLPSGESMVRQFLHGQNFFKDEFGNYCKEFWL 380

  Fly   267 IDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQRQLEFLWRQIWDNKGDTALFTHMMPFY 331
            .|.||:|..:|.|::..|....:.|:..:::.......   .|.|..|    ..||:.||..|..
Zfish   381 PDTFGYSAQLPQIMKGCGISRFITQKLSWNLINTFPHN---TFFWEGI----DGTAVLTHFPPGN 438

  Fly   332 SYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVDQWKKKAELYRTN 396
            ||:                                        :..:.:.|::..|...:..|.|
Zfish   439 SYE----------------------------------------MKGKVEDLINTVKNNKDKGRAN 463

  Fly   397 --VLLIPLGDD---------FRFKQNTEWD----VQRVNYERLFEHINSQAHFNVQAQFGTLQEY 446
              .||...||.         .|..:..:.|    ||....:.||.|:.|.:....:    .:.|.
Zfish   464 HSALLFGFGDGGGGPTQLMLDRLHRVKDTDCLPKVQMSTPDVLFSHLESDSSLLCR----WVGEL 524

  Fly   447 FDAVHQAERAGQAEFPTLSGDFFTYADRSDNYWSGYYTSRPYHKRMDR---VLMHYVRAAEMLSA 508
            |..:|                            :|.||::...|..:|   .|:|.|..|..| |
Zfish   525 FLELH----------------------------NGTYTTQAKIKMKNRQCETLLHDVEVASCL-A 560

  Fly   509 WHSWDGMARIEERLEQARRELSLFQHHDGITGTAKTHVVVDYEQRMQE--------ALKACQMVM 565
            ....|.......||::..|.|.|.|.||.|.|:....||.|..|...|        .|.||:.:
Zfish   561 LSKKDSFKYPACRLQELWRLLLLNQFHDVIPGSCIGMVVEDALQYYDEIHTTASRLLLDACKSL- 624

  Fly   566 QQSVYRLLTKPSIYSPDFSFSYFTLDDSRW----------------------PGSGVEDSRTTII 608
                      ||  |||...:  .|:...|                      |..||...:.|..
Zfish   625 ----------PS--SPDNGIA--VLNTLSWERTEVISLPMKDTETRLALVRVPSVGVAHVKETAE 675

  Fly   609 LGEDILPSKHV----VMHN-----TLPHW------------REQLVDFYVSSPFVSVTDLANNPV 652
            ..|.::.:..|    :|.|     |:.|.            ||.:.:....:.|....|:   |:
Zfish   676 SAESVIATMMVNGTIIMENGLLKATIDHLGRLMSLLLIQTNRETISEGCFGNQFALFDDV---PL 737

  Fly   653 EAQVSPVWSWHHDT---LTKTIHPQ--------------------GSTTKYRIIFKARVPPMGLA 694
            ......|..:|..|   :.:.|.|.                    .||.:..|:..|..|.:...
Zfish   738 YWDAWDVMDYHLQTRKPVIEVIEPAKVLKSGGIQASVSFSLRINGKSTIQQEIVLDACCPYIKFK 802

  Fly   695 TYVLTISDSKPEHTSYASNLLLRKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAF------- 752
            |:|:         ...|...|..:.|..:...:...:::||..:..:.|..:.....|
Zfish   803 THVV---------WEEAHKFLKVEFPVQVRSPEATYEIQFGHLQRPTHRNTSWDWARFEVWGHKW 858

  Fly   753 ---SEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSH---------------------GDRSGAYLF 793
               ||.|.  .:.|..||          |||...|                     ||...:|..
Zfish   859 ADLSEHGF--GVALLNDS----------KYGYSVHQNIMTLSLLRAPKAPDLNADMGDHIFSYAL 911

  Fly   794 LPNGPA--------------SPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLV 844
            :|:...              .|:.:...|:    .|..|:.||..|:::.:||.:....|...|:
Zfish   912 MPHTGTFQESAVIQYAYNFNYPLRVHHGVI----PKPWSAFSVSSPAIILETIKKAEKRENALLI 972

  Fly   845 DIGSLDNTEIVMRLETHIDSGDIFYTDL 872
            .:.....:.:.:.|.|.....::::.||
Zfish   973 RLYESHGSRVTVTLSTSFLLQEVWHCDL 1000

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-IIa	NP_001262413.1	PLN02701	105..990	CDD:178304	166/873 (19%)
		Glyc_hyd_38C_2	1020..1108	CDD:408054
man2c1	XP_009296368.1	MngB	256..1031	CDD:440152	166/873 (19%)