Protein Alignment alpha-Man-IIa and ams1

DIOPT Version :10

• Sequence 1: NP_001262413.1
• Gene: alpha-Man-IIa / 41126
• FlyBaseID: FBgn0011740
• Length: 1109
• Species: Drosophila melanogaster
• Sequence 2: NP_593979.1
• Gene: ams1 / 2543485
• PomBaseID: SPAC513.05
• Length: 1077
• Species: Schizosaccharomyces pombe
• Alignment Length: 906
• Identity: 176/906 - (19%)
• Similarity: 309/906 - (34%)
• Gaps: 276/906 - (30%)

  Fly   144 KLKVFVVPHSHNDPGWIQTFEE------------------YYQHDTKHILSNALRHL---HDNPE 187
            |..||.:.|.|.|..|:..|.|                  |.::  :.:.|.||::|   .|:|:
pombe   280 KANVFAIGHCHIDTAWLWPFAETRRKIVRSWATQMNIMDRYPEY--QFVCSQALQYLWLKEDHPD 342

  Fly   188 MKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEFVTGGWVMPDEANSHWRNVLLQLTEGQTW 252
            :         |.:....:.:||.:.            :.|.||..|....:..:::.|...||.:
pombe   343 V---------FEKLKEYVNQNKFIP------------IGGSWVEHDTNIPNGESLIRQFLLGQHF 386

  Fly   253 LKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQRQLEFLWRQI--- 314
            .::...|.....|..|.||:|..:|.|.:..|....|.|:                ..|..|
pombe   387 FEKEFGVRCRTFWLPDTFGYSSQIPQICRLCGMDRFLTQK----------------LSWNNINSF 435

  Fly   315 ------WDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQ 373
                  |.....:.:..||.|..:|                                    .:|.
pombe   436 PTSTFNWVALDGSQVICHMPPANTY------------------------------------TADT 464

  Fly   374 NVAARSDLL--VDQWKKKAELYRTNVLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNV 436
            ||   :|:|  :||.|.... .:..:|:..:||.     ......:.:...|..:.|.:...:..
pombe   465 NV---NDVLHSIDQHKNLVN-DQAGLLVFGIGDG-----GGGPTPEMLEKLRRCKGIANTVGYLP 520

  Fly   437 QAQFG-TLQEYFDAVHQAERAGQAEFPTLSGDFFTYADRSDNYWSGYYTSRPYHKRMDR---VLM 497
            ..:.| |:.|:||.:.:...|||. .|:.:|:.:.      .:..|.||::...|::.|   :.:
pombe   521 NVKLGNTVDEFFDGILKRTNAGQT-LPSWNGELYF------EFHRGTYTTQAELKKLMRKVEIAL 578

  Fly   498 HYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKTHVVVDYEQRMQEALKACQ 562
            |.......|::..|.| .:..:|.|:...|:..|.|.||.:.|:....|..|....|.:.||..:
pombe   579 HDAEYVSTLASIFSKD-YSYPKESLQDLWRDTLLCQFHDVLPGSCIEMVYKDAIPIMSKVLKNTE 642

  Fly   563 MVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGV--EDSRTTIIL-----GEDILPSKHVV 620
            .::.|::.:|..|.: .|.|.......|:...|...||  |.....::.     |:.||.:.|..
pombe   643 ALLWQAIEQLGFKKA-SSSDNKEQLCLLNTLPWNVRGVITETEENKLVYFESCDGKGILTAAHTS 706

  Fly   621 MHNTLPHWREQ----LVDFYV------SSPFVSVTDL-----------------ANNPVEAQVSP 658
            :.:....:::.    ||:.::      :...:|:.||                 ||..|..:.:|
pombe   707 LKHPAAAYQKDDNFILVNDHLRVTIAPNGLILSLFDLHKEREILDLKSGKNHAGANQYVLFEDTP 771

  Fly   659 V-W-SWHHDTLTKTIHPQGSTTKYRIIFKARV----------------PPMGLATYVLTIS---- 701
            : | :|..:..        |..||.::.|.:|                |...|:....|||
pombe   772 LSWQAWDTEVF--------SLEKYEVLDKGKVSIKESGPLRASVVVDIPISELSHMKATISLEGY 828

  Fly   702 ------------------------------DSKPEHTSYASNLLLRKNP----TSLPLGQYPEDV 732
                                          |...|..||.:...:.|.|    ||..:.::  :|
pombe   829 NDCSEFTGVNFTCEVDWHESCKFLKVEFPVDIHSEFASYETQFGITKRPTHYNTSWDVAKF--EV 891

  Fly   733 ---KFGDPREISLRVG--NGPTLAFSEQGLLKSIQL----TQDSPHVPVHFKFLKYGVRSHG--- 785
               ||.|..:.:..|.  |.....||..|.|..:.|    .|...|..:....::|.|..|.
pombe   892 CHQKFADYSDFTYGVSVLNDCKYGFSTHGNLMRLSLLRSPKQPDAHADMGKHTIRYAVYPHSKPL 956

  Fly   786 DRS---GAYLFLPNGPASPVELGQPVVLVTKGKLESSVS-------VGLPSVVHQTIM---RGGA 837
            |.|   .|:.|..|           ..|:|:....:::.       ||.|:|:...|.   :|.:
pombe   957 DSSTVRAAHKFNSN-----------FRLLTRASDTANLDIFDAFQLVGEPNVILSHIKMAEKGKS 1010

  Fly   838 PEIRNLVDIGSLDNTEIVMRLETHIDSGDIFYTDLNGLQFIKRRRLDKL-PLQAN-YYPIP 896
            ..:|....:|......:|::..|...     .|..|||:    ..|::| .|::| ||.:|
pombe  1011 IILRVYESLGGKSRARLVIKSLTVAS-----VTKCNGLE----EDLEELCTLKSNDYYEVP 1062

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-IIa	NP_001262413.1	PLN02701	105..990	CDD:178304	176/906 (19%)
		Glyc_hyd_38C_2	1020..1108	CDD:408054
ams1	NP_593979.1	MngB	282..1075	CDD:440152	175/904 (19%)