Protein Alignment Task7 and Kcnk16

DIOPT Version :10

• Sequence 1: NP_649891.1
• Gene: Task7 / 41125
• FlyBaseID: FBgn0037690
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_083282.1
• Gene: Kcnk16 / 74571
• MGIID: 1921821
• Length: 292
• Species: Mus musculus
• Alignment Length: 244
• Identity: 77/244 - (31%)
• Similarity: 126/244 - (51%)
• Gaps: 12/244 - (4%)

  Fly     8 RTLSLVVCTFTYLLIGAAVFDSLESPTEAKRWEFLQTVKNNFVRKYNVTDEDF--RVMEIVI--- 67
            :.|.|::....|||:||.:|..||...||:..:..|..|..|:..|...|:..  :.:::::
Mouse    13 QVLPLLLAYICYLLLGATIFQLLEKQAEAQSRDQFQLEKLRFLENYTCLDQQALEQFVQVILEAW 77

  Fly    68 ---IENKPHKAGP-QWKFAGAFYFSTVVLAMIGYGHSTPVTIPGKAFCMGYAMVGIPLGLVMFQS 128
               :..|.:...| .|.|..:|:|:..|:..||||:..|.|..|:.||:.||::||||.:|....
Mouse    78 VKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALMGIPLNVVFLNH 142

  Fly   129 IGERLNKFASVIIRRAKRASGARCTDATEMNLMLATGMLSSIIITTGAAVFSRYEGWSYFDSFYY 193
            :|..|....:.:.|.......::......:.|.|..|.|  :|:......||..||||:.:.||:
Mouse   143 LGTGLRAHLTTLDRWEDHPRHSQLLQVLGLALFLTLGTL--VILIFPPMFFSHVEGWSFREGFYF 205

  Fly   194 CFVTLTTIGFGDYVALQNDQALTNKPGYVALSLVFILFGLAVVAASINL 242
            .|:||:|||||||| :..|.:......|.:|:.::||.|||.:|..::|
Mouse   206 AFITLSTIGFGDYV-VGTDPSKHYIAVYRSLAAIWILLGLAWLAVVLSL 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Task7	NP_649891.1	Ion_trans_2	<74..133	CDD:462301	23/59 (39%)
		Ion_trans_2	166..244	CDD:462301	31/77 (40%)
Kcnk16	NP_083282.1	Ion_trans_2	87..145	CDD:462301	22/57 (39%)
		Selectivity filter 1. /evidence=ECO:0000250|UniProtKB:Q96T55	108..113		3/4 (75%)
		Ion_trans_2	180..248	CDD:462301	29/70 (41%)
		Selectivity filter 2. /evidence=ECO:0000250|UniProtKB:Q96T55	212..217		4/4 (100%)