Protein Alignment Task7 and KCNK10

DIOPT Version :10

• Sequence 1: NP_649891.1
• Gene: Task7 / 41125
• FlyBaseID: FBgn0037690
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_612190.1
• Gene: KCNK10 / 54207
• HGNCID: 6273
• Length: 543
• Species: Homo sapiens
• Alignment Length: 316
• Identity: 89/316 - (28%)
• Similarity: 149/316 - (47%)
• Gaps: 45/316 - (14%)

  Fly     1 MMKRQNVRTLSLVVCTFTYLLIGAAVFDSLESPTEAKRWEFLQTVKNNFVRKY-NVTDEDFRVME 64
            :||.:.|  :::.|....||:.|..||.:||.|.|:.:...:...|..|:|.: .|:.::   :|
Human    71 VMKWKTV--VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQE---LE 130

  Fly    65 IVI-------------IENKPHKAGPQWKFAGAFYFSTVVLAMIGYGHSTPVTIPGKAFCMGYAM 116
            .:|             |.|..:.:. .|....||:|:..|:..||||:..|.|..||.||:.||:
Human   131 TLIQHALDADNAGVSPIGNSSNNSS-HWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAI 194

  Fly   117 VGIPLGLVMFQSIGERLNKFASVIIRRAKRASGARCTDATEMN-----LMLATGMLSSIIITTGA 176
            .||||...:...||::|.......|.|.::....:....|::.     |.:..|.:  :.:|..|
Human   195 FGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCI--VFVTIPA 257

  Fly   177 AVFSRYEGWSYFDSFYYCFVTLTTIGFGDYVALQNDQALTNKPGYVALSLVFILFGLAVVAASIN 241
            .:|...|||:..:|.|:..|||||:||||:||..| ..:..:..|..|...:||.|||..||.::
Human   258 VIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGN-AGINYREWYKPLVWFWILVGLAYFAAVLS 321

  Fly   242 LL--VLRFMTMQAEDAKRDEQDAQNLAGNAQP----VTFDDEST-----YNMHGKL 286
            ::  .||.:      :|:.:::...:..:|..    ||.:...|     ..:|.||
Human   322 MIGDWLRVL------SKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKL 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Task7	NP_649891.1	Ion_trans_2	<74..133	CDD:462301	23/58 (40%)
		Ion_trans_2	166..244	CDD:462301	29/79 (37%)
KCNK10	NP_612190.1	Ion_trans_2	<153..211	CDD:462301	23/58 (40%)
		Ion_trans_2	249..328	CDD:462301	29/81 (36%)