Protein Alignment Task7 and KCNC2

DIOPT Version :10

• Sequence 1: NP_649891.1
• Gene: Task7 / 41125
• FlyBaseID: FBgn0037690
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_631875.1
• Gene: KCNC2 / 3747
• HGNCID: 6234
• Length: 638
• Species: Homo sapiens
• Alignment Length: 164
• Identity: 36/164 - (21%)
• Similarity: 65/164 - (39%)
• Gaps: 42/164 - (25%)

  Fly   191 FYYCFVTLTTIGFGDYVALQNDQALTNKPGYVALSLVFILFGLAVVAASINLLVLRF-----MTM 250
            |::..||:||:|:||    ...|..:.    :.:..:..|.|:..:|..:.::|..|     :.|
Human   428 FWWAVVTMTTLGYGD----MYPQTWSG----MLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAM 484

  Fly   251 QAEDAKRDEQDAQNLAGNAQPVTFDDESTYNMHGKLLENNYTTENDETASLCSCTCMG-GTRCLN 314
            ..:...|..:.....|..|...|| .::..||...      :|::|        ||:| ..|.|.
Human   485 AKQKLPRKRKKHIPPAPQASSPTF-CKTELNMACN------STQSD--------TCLGKDNRLLE 534

  Fly   315 HEQFV---------DPDFQPTDIIESTLCLKRAS 339
            |.:.|         :|...|.:    .|.::|:|
Human   535 HNRSVLSGDDSTGSEPPLSPPE----RLPIRRSS 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Task7	NP_649891.1	Ion_trans_2	<74..133	CDD:462301
		Ion_trans_2	166..244	CDD:462301	12/52 (23%)
KCNC2	NP_631875.1	BTB_KCNC2_4	7..166	CDD:349722
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	38..93
		Ion_trans	228..484	CDD:459842	14/63 (22%)
		Selectivity filter. /evidence=ECO:0000250	437..442		2/4 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	538..572		6/31 (19%)