Protein Alignment Task7 and Kcna3

DIOPT Version :10

• Sequence 1: NP_649891.1
• Gene: Task7 / 41125
• FlyBaseID: FBgn0037690
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_062143.3
• Gene: Kcna3 / 29731
• RGDID: 2951
• Length: 525
• Species: Rattus norvegicus
• Alignment Length: 197
• Identity: 43/197 - (21%)
• Similarity: 79/197 - (40%)
• Gaps: 34/197 - (17%)

  Fly   140 IIRRAKRASGARCTDATEMNLMLATGML-----SSIIITTGAAVFSRYE----GW-SYFDSFYYC 194
            |.:.::.:.|.:....|....|...|:|     ..:|:.:.|..|:..:    |: |..|:|::.
  Rat   324 IFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPSSGFNSIPDAFWWA 388

  Fly   195 FVTLTTIGFGDY--VALQNDQALTNKPGYVALSLVFILFGLAVVAASINLLVLRFMTMQAEDAKR 257
            .||:||:|:||.  |.:         .|.:..||..|. |:..:|..:.::|..|......:.:.
  Rat   389 VVTMTTVGYGDMHPVTI---------GGKIVGSLCAIA-GVLTIALPVPVIVSNFNYFYHRETEG 443

  Fly   258 DEQDAQNLAGNAQPVTFDDESTYNMHGKLLENNYTTENDETASLCSCTCMGGTRCLNHEQFVDPD 322
            :||......|:.|.::...|..     :...:|.|....|...:..    ||   :||..|....
  Rat   444 EEQAQYMHVGSCQHLSSSAEEL-----RKARSNSTLSKSEYMVIEE----GG---MNHSAFPQTP 496

  Fly   323 FQ 324
            |:
  Rat   497 FK 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Task7	NP_649891.1	Ion_trans_2	<74..133	CDD:462301
		Ion_trans_2	166..244	CDD:462301	22/89 (25%)
Kcna3	NP_062143.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23
		BTB_POZ	54..180	CDD:453885
		Ion_trans	183..440	CDD:459842	29/125 (23%)
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	394..399		2/4 (50%)
		Interaction with KCNE4. /evidence=ECO:0000269|PubMed:27802162	432..525		15/79 (19%)
		PDZ-binding. /evidence=ECO:0000269|PubMed:7477295	523..525