Protein Alignment Task7 and twk-23

DIOPT Version :10

• Sequence 1: NP_649891.1
• Gene: Task7 / 41125
• FlyBaseID: FBgn0037690
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001257229.1
• Gene: twk-23 / 192071
• WormBaseID: WBGene00006676
• Length: 443
• Species: Caenorhabditis elegans
• Alignment Length: 279
• Identity: 83/279 - (29%)
• Similarity: 127/279 - (45%)
• Gaps: 51/279 - (18%)

  Fly     2 MKRQNVRTLSL--------VVCTFTYLLIGAAVFDSLESPTEA----KRWEFLQTVKNNFVRKYN 54
            ||.:||..::|        |||   |:..||.||..||...|.    |:.|:...:|.:.:.|..
 Worm    33 MKFRNVLRIALGHLALYCFVVC---YVFAGAWVFHQLEGENETELHDKQREYAMNLKKDVIAKLA 94

  Fly    55 VTD------EDFRV-----------MEIVIIENKPHKAGP-QWKFAGAFYFSTVVLAMIGYGHST 101
            .|:      |..|:           ::..:|.|:|.:..| :|.|..:..||..:|..||||:.|
 Worm    95 TTENVAEINEHLRMFLRNISNLHISLDNYLIFNEPTQIVPKRWTFPSSVLFSFTILTTIGYGNVT 159

  Fly   102 PVTIPGKAFCMGYAMVGIPLGLVMFQSIGERLNKFASVII------RRAKRASGARCTDATEMNL 160
            |.|...|.|.|.|...||||.|:....:| |.:|.|.:.:      |..|:.|....  ..|:..
 Worm   160 PHTQQCKVFLMIYGAFGIPLFLITIADLG-RFSKTAIMALVQKVSKRELKKQSDEHL--LREIAE 221

  Fly   161 MLATGMLSSIIITTGAAVFSRYEG-WSYFDSFYYCFVTLTTIGFGDYVALQNDQALTNKPGYVAL 224
            :|....|..:.|..|:||...:|. .:||||.|:.:::|||||.||.|..:.|        ::..
 Worm   222 VLLVAGLFVVFIAIGSAVIPLWENQLTYFDSVYFSYMSLTTIGLGDIVPRRMD--------FLLP 278

  Fly   225 SLVFILFGLAVVAASINLL 243
            :|::|..||.:..|.:..|
 Worm   279 TLIYITIGLWLTTALVEQL 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Task7	NP_649891.1	Ion_trans_2	<74..133	CDD:462301	23/59 (39%)
		Ion_trans_2	166..244	CDD:462301	26/79 (33%)
twk-23	NP_001257229.1	Ion_trans_2	<136..190	CDD:462301	22/54 (41%)
		Ion_trans_2	224..302	CDD:462301	26/82 (32%)