Protein Alignment Task7 and Kcna3

DIOPT Version :10

• Sequence 1: NP_649891.1
• Gene: Task7 / 41125
• FlyBaseID: FBgn0037690
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_032444.2
• Gene: Kcna3 / 16491
• MGIID: 96660
• Length: 528
• Species: Mus musculus
• Alignment Length: 197
• Identity: 43/197 - (21%)
• Similarity: 79/197 - (40%)
• Gaps: 34/197 - (17%)

  Fly   140 IIRRAKRASGARCTDATEMNLMLATGML-----SSIIITTGAAVFSRYE----GW-SYFDSFYYC 194
            |.:.::.:.|.:....|....|...|:|     ..:|:.:.|..|:..:    |: |..|:|::.
Mouse   327 IFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPSSGFNSIPDAFWWA 391

  Fly   195 FVTLTTIGFGDY--VALQNDQALTNKPGYVALSLVFILFGLAVVAASINLLVLRFMTMQAEDAKR 257
            .||:||:|:||.  |.:         .|.:..||..|. |:..:|..:.::|..|......:.:.
Mouse   392 VVTMTTVGYGDMHPVTI---------GGKIVGSLCAIA-GVLTIALPVPVIVSNFNYFYHRETEG 446

  Fly   258 DEQDAQNLAGNAQPVTFDDESTYNMHGKLLENNYTTENDETASLCSCTCMGGTRCLNHEQFVDPD 322
            :||......|:.|.::...|..     :...:|.|....|...:..    ||   :||..|....
Mouse   447 EEQAQYMHVGSCQHLSSSAEEL-----RKARSNSTLSKSEYMVIEE----GG---MNHSAFPQTP 499

  Fly   323 FQ 324
            |:
Mouse   500 FK 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Task7	NP_649891.1	Ion_trans_2	<74..133	CDD:462301
		Ion_trans_2	166..244	CDD:462301	22/89 (25%)
Kcna3	NP_032444.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..32
		BTB_POZ	57..183	CDD:453885
		Ion_trans	186..443	CDD:459842	29/125 (23%)
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	397..402		2/4 (50%)
		Interaction with KCNE4. /evidence=ECO:0000250|UniProtKB:P15384	435..528		15/79 (19%)
		PDZ-binding. /evidence=ECO:0000250|UniProtKB:P15384	526..528