Protein Alignment betaTub85D and TUBA1C

DIOPT Version :9

• Sequence 1: NP_524290.2
• Gene: betaTub85D / 41124
• FlyBaseID: FBgn0003889
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_001290043.1
• Gene: TUBA1C / 84790
• HGNCID: 20768
• Length: 519
• Species: Homo sapiens
• Alignment Length: 454
• Identity: 183/454 - (40%)
• Similarity: 269/454 - (59%)
• Gaps: 21/454 - (4%)

  Fly     2 REIVHIQAGQCGNQIGGKFWEVISDEHCIDATG------TYYGDSDLQLERINVYYNEATGAKYV 60
            ||.:.|..||.|.|||...||:...||.|...|      |..|..|    ..|.:::|....|:|
Human    72 RECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDD----SFNTFFSETGAGKHV 132

  Fly    61 PRAILVDLEPGTMDSVRSGAFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESE 125
            |||:.|||||..:|.||:|.:.|:|.|:..:.|:..|.||:|:||||.|.|::|.|||.:||.::
Human   133 PRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLAD 197

  Fly   126 GCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVH 190
            .|..||||.:.||.|||||||..:||:.::..:|..:....||:.|:|:||..||||||:.|:.|
Human   198 QCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTH 262

  Fly   191 QLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAV 255
            ..:|::|..:.:||||:||||.|.|.:..|||.:||.|:|..:|.:|..|||.|.||.||.:...
Human   263 TTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQT 327

  Fly   256 NMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGR 320
            |:||:||:||.:..:||:.|.....:..|||.|:|...|:..|.|..||||||:|:....::||.
Human   328 NLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGD 392

  Fly   321 MSMKEVDEQMLNIQNKNSSFFVEWIPNNCKTAVCDIPP--------RGLKMSATFIGNSTAIQEL 377
            :..|:|:..:..|:.|.:..||:|.|...|..:...||        ..::.:...:.|:||:.|.
Human   393 VVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAVAEA 457

  Fly   378 FKRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADEEGEFDEDEE 441
            :.|:..:|..|:.::||:|||.||||:|.||:||..:|..|..:|::....:||.|   ||.||
Human   458 WARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSADGE---DEGEE 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub85D	NP_524290.2	PLN00220	1..430	CDD:215107	176/441 (40%)
TUBA1C	NP_001290043.1	PTZ00335	72..518	CDD:185562	181/452 (40%)
		alpha_tubulin	72..505	CDD:276955	176/436 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810