Protein Alignment betaTub85D and TUBB1

DIOPT Version :9

• Sequence 1: NP_524290.2
• Gene: betaTub85D / 41124
• FlyBaseID: FBgn0003889
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_110400.1
• Gene: TUBB1 / 81027
• HGNCID: 16257
• Length: 451
• Species: Homo sapiens
• Alignment Length: 450
• Identity: 346/450 - (76%)
• Similarity: 393/450 - (87%)
• Gaps: 8/450 - (1%)

  Fly     1 MREIVHIQAGQCGNQIGGKFWEVISDEHCIDATGTYYGDSDLQLERINVYYNEATGAKYVPRAIL 65
            ||||||||.||||||||.||||:|.:||.||..|:..|.|.||||||:||||||.|.||||||:|
Human     1 MREIVHIQIGQCGNQIGAKFWEMIGEEHGIDLAGSDRGASALQLERISVYYNEAYGRKYVPRAVL 65

  Fly    66 VDLEPGTMDSVRSGAFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESEGCDCL 130
            ||||||||||:||...|.:|:||:||.|.||||||||||||||||||:::||:|||.|||.||||
Human    66 VDLEPGTMDSIRSSKLGALFQPDSFVHGNSGAGNNWAKGHYTEGAELIENVLEVVRHESESCDCL 130

  Fly   131 QGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVEN 195
            ||||:.|||||||||||||||::||||||||||||:|||:|||||||||||||||.||:|||:||
Human   131 QGFQIVHSLGGGTGSGMGTLLMNKIREEYPDRIMNSFSVMPSPKVSDTVVEPYNAVLSIHQLIEN 195

  Fly   196 TDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPF 260
            .|..:||||||||||||||||||||||||||||||.||||:||.|||||||||||||||||||||
Human   196 ADACFCIDNEALYDICFRTLKLTTPTYGDLNHLVSLTMSGITTSLRFPGQLNADLRKLAVNMVPF 260

  Fly   261 PRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKE 325
            ||||||||||||||::||||||||:|.|||||||||:|.|||||.|.|||||||.||||:||.||
Human   261 PRLHFFMPGFAPLTAQGSQQYRALSVAELTQQMFDARNTMAACDLRRGRYLTVACIFRGKMSTKE 325

  Fly   326 VDEQMLNIQNKNSSFFVEWIPNNCKTAVCDIPPRGLKMSATFIGNSTAIQELFKRVSEQFTAMFR 390
            ||:|:|::|.:|||.||||||||.|.||||||||||.|:||||||:|||||:|.||||.|:|||:
Human   326 VDQQLLSVQTRNSSCFVEWIPNNVKVAVCDIPPRGLSMAATFIGNNTAIQEIFNRVSEHFSAMFK 390

  Fly   391 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATA--------DEEGEFDEDEEG 442
            ||||:||||.||||..||.|||:|::||||||||:|:|.|        .||.|.:.:::|
Human   391 RKAFVHWYTSEGMDINEFGEAENNIHDLVSEYQQFQDAKAVLEEDEEVTEEAEMEPEDKG 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub85D	NP_524290.2	PLN00220	1..430	CDD:215107	341/428 (80%)
TUBB1	NP_110400.1	PTZ00010	1..428	CDD:240228	340/426 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	432..451		3/18 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D259639at33208
OrthoFinder	1	1.000	-	-		FOG0000096
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100137
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X99
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.720